The infrapatellar fat pad produces interleukin‐6‐secreting T cells in response to a proteoglycan aggrecan peptide and provides dominant soluble mediators different from that present in synovial fluid

Author:

Sae‐jung Thitiya1,Leearamwat Nitigorn2,Chaiseema Nichakarn2,Sengprasert Panjana1,Ngarmukos Srihatach3,Yuktananda Pongsak3,Tanavalee Aree34,Hirankarn Nattiya25,Reantragoon Rangsima25ORCID

Affiliation:

1. Medical Microbiology Interdisciplinary Program Graduate School Chulalongkorn University Bangkok Thailand

2. Immunology Division Department of Microbiology Faculty of Medicine Chulalongkorn University Bangkok Thailand

3. Department of Orthopedics Faculty of Medicine Chulalongkorn University Bangkok Thailand

4. Osteoarthritis and Musculoskeletal Research Unit Faculty of Medicine Chulalongkorn University Bangkok Thailand

5. Center of Excellence in Immunology and Immune‐mediated Diseases Faculty of Medicine Chulalongkorn University Bangkok Thailand

Publisher

Wiley

Subject

Rheumatology

Reference62 articles.

1. Low‐grade inflammation as a key mediator of the pathogenesis of osteoarthritis;Robinson WH;Nat Rev Rheumatol,2016

2. Epidemiology of osteoarthritis;Neogi T;Rheum Dis Clin North Am,2013

3. Osteoarthritis: a disease of the joint as an organ;Loeser RF;Arthritis Rheum,2012

4. Immunopathogenesis of osteoarthritis;Haseeb A;Clin Immunol,2013

5. Synovial inflammation, immune cells and their cytokines in osteoarthritis: a review;de Lange‐Brokaar B;Osteoarthritis Cartilage,2012

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