Expression of a Chimeric Antigen Receptor Specific for Donor HLA Class I Enhances the Potency of Human Regulatory T Cells in Preventing Human Skin Transplant Rejection-Reference-Cited by-同舟云学术

Expression of a Chimeric Antigen Receptor Specific for Donor HLA Class I Enhances the Potency of Human Regulatory T Cells in Preventing Human Skin Transplant Rejection

Published:2017-02-01 Issue:4 Volume:17 Page:931-943
ISSN:1600-6135
Container-title:American Journal of Transplantation
language:en
Short-container-title:Am J Transplant

Author:

Boardman D. A.¹²,Philippeos C.³,Fruhwirth G. O.⁴,Ibrahim M. A. A.⁵⁶,Hannen R. F.⁷,Cooper D.⁸,Marelli-Berg F. M.⁸,Watt F. M.²³,Lechler R. I.¹²,Maher J.²⁵⁹,Smyth L. A.¹¹⁰,Lombardi G.¹²

Affiliation:

1. MRC Centre for Transplantation; King's College London; Guy's Hospital; London UK

2. NIHR Biomedical Research Centre; Guy's & St Thomas’ NHS Foundation Trust & King's College London; Guy's Hospital; London UK

3. Centre for Stem Cells & Regenerative Medicine; King's College London; Guy's Hospital; London UK

4. Department of Imaging Chemistry and Biology; Division of Imaging Sciences and Biomedical Engineering; King's College London; St. Thomas’ Hospital; London UK

5. Department of Clinical Immunology and Allergy; King's College London; King's College Hospital; London UK

6. Division of Asthma, Allergy & Lung Biology; King's College London; Guy's Hospital; London UK

7. Centre for Cell Biology & Cutaneous Research; Bart's and The London School of Medicine and Dentistry; Queen Mary University of London; London UK

8. William Harvey Research Institute; Bart's and The London School of Medicine; Queen Mary University of London; London UK

9. CAR Mechanics Group; Division of Cancer Studies; King's College London; Guy's Hospital; London UK

10. School of Health, Sport and Bioscience; Stratford Campus; University of East London; London UK

Funder

NIHR BRC Guy's and St Thomas’ NHS Foundation Trust

Department of Health via the National Institute for Health Research Comprehensive Biomedical Research Centre

Guy's and St Thomas' NHS Foundation Trust

King's College London

King's College Hospital NHS Foundation Trust

British Heart Foundation

Medical Research Council

Publisher

Wiley

Subject

Pharmacology (medical),Transplantation,Immunology and Allergy

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/ajt.14185/fullpdf

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3. Relevance of regulatory T cell promotion of donor-specific tolerance in solid organ transplantation;Sagoo;Front Immunol,2012

4. Indefinite mouse heart allograft survival in recipient treated with CD4(+)CD25(+) regulatory T cells with indirect allospecificity and short term immunosuppression;Tsang;Transpl Immunol,2009

5. Allorecognition;Rogers;Am J Transplant,2001

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