FASN inhibition sensitizes metastatic OSCC cells to cisplatin and paclitaxel by downregulating cyclin B1-Reference-Cited by-同舟云学术

FASN inhibition sensitizes metastatic OSCC cells to cisplatin and paclitaxel by downregulating cyclin B1

Published:2021-09-29 Issue: Volume: Page:
ISSN:1354-523X
Container-title:Oral Diseases
language:en
Short-container-title:Oral Dis

Author:

Almeida Luciana Yamamoto de¹^ORCID,Moreira Fernanda dos Santos¹,Santos Guilherme Augusto Silva dos²^ORCID,Cuadra Zelaya Florence Juana Maria¹,Ortiz César Alexander³^ORCID,Agostini Michelle⁴^ORCID,Mariano Flávia Sammartino¹,Bastos Débora Campanella⁵^ORCID,Daher Ulisses Ribaldo Nicolau⁶⁷,Kowalski Luiz Paulo⁸⁹^ORCID,Coletta Ricardo D.¹^ORCID,Graner Edgard¹^ORCID

Affiliation:

1. Department of Oral Diagnosis Piracicaba Dental School State University of Campinas (UNICAMP) Piracicaba Brazil

2. School of Medicine University of Ribeirão Preto (UNAERP) Ribeirão Preto Brazil

3. Hematology Division, Department of Medical Images, Hematology, and Clinical Oncology University of São Paulo at Ribeirão Preto Medical School Ribeirão Preto Brazil

4. Department of Oral Diagnosis and Pathology, School of Dentistry Federal University of Rio de Janeiro (UFRJ) Rio de Janeiro Brazil

5. Department of Biosciences, Piracicaba Dental School State University of Campinas (UNICAMP) Piracicaba Brazil

6. Department of Clinical Oncology, A. C. Camargo Cancer Center São Paulo Brazil

7. Department of Clinical Oncology Hospital Amaral Carvalho São Paulo Brazil

8. Department of Otorhinolaryngology and Head and Neck Surgery A. C. Camargo Cancer Center São Paulo Brazil

9. Department of Head and Neck Surgery Medical School, University of São Paulo São Paulo Brazil

Funder

Fundação de Amparo à Pesquisa do Estado de São Paulo

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Wiley

Subject

General Dentistry,Otorhinolaryngology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/odi.14017

Reference58 articles.

1. The Fatty Acid Synthase Inhibitor Orlistat Reduces the Growth and Metastasis of Orthotopic Tongue Oral Squamous Cell Carcinomas

2. Fatty acid synthase regulates the chemosensitivity of breast cancer cells to cisplatin-induced apoptosis

3. Targeting cyclin B1 inhibits proliferation and sensitizes breast cancer cells to taxol

4. Anticancer properties of the fatty acid synthase inhibitor TVB-3166 on oral squamous cell carcinoma cell lines

5. Fatty acid synthase overexpression: target for therapy and reversal of chemoresistance in ovarian cancer

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