Changing patterns of care for pancreas cancer in Victoria: the 2022 Pancreas Tumour Summit

Author:

Pilgrim Charles H. C.123ORCID,Finn Norah45,Stuart Ella45,Philip Jennifer678,Steel Simone91011,Croagh Dan121314,Lee Belinda15161718,Tebbutt Niall C.19

Affiliation:

1. Hepatopancreaticobiliary Surgery The Alfred Hospital Melbourne Victoria Australia

2. Department of Surgery Central Clinical School, Monash University Victoria Australia

3. School of Public Health and Preventative Medicine Monash University Victoria Australia

4. Victorian Cancer Registry Cancer Council Victoria Melbourne Victoria Australia

5. Department of Health Cancer Support, Treatment and Research Melbourne Victoria Australia

6. Department of Medicine University of Melbourne Parkville Victoria Australia

7. Palliative Care Service St Vincent's Hospital Fitzroy Victoria Australia

8. Palliative Care Service Peter MacCallum Cancer Centre Parkville Victoria Australia

9. Department of Medical Oncology Eastern Health Box Hill Victoria Australia

10. Eastern Health Clinical School Monash University Melbourne Victoria Australia

11. Department of Medical Oncology Peninsula Private Hospital Langwarrin Victoria Australia

12. Department of Surgery, Faculty of Medicine, Nursing and Health Sciences Monash University Clayton Victoria Australia

13. Department of Surgery Monash Medical Centre, Monash Health Clayton Victoria Australia

14. Department of Surgery St Vincent's Hospital Melbourne Melbourne Victoria Australia

15. Department of Medical Oncology Peter MacCallum Cancer Centre Parkville Victoria Australia

16. Department of Medical Oncology Northern Health Epping Victoria Australia

17. Division of Personalised Oncology Walter & Eliza Hall Institute Parkville Victoria Australia

18. Faculty of Medicine, Dentistry & Health Science University of Melbourne Parkville Victoria Australia

19. Department of Medical Oncology Austin Health Heidelberg Victoria Australia

Abstract

AbstractBackgroundThe Victorian Government convened the second Pancreas Cancer Summit in 2021 to identify unwarranted variation in care 2016–2019, and to assess trends compared with the first Summit 2017 (reporting 2011–2015). State‐wide administrative data were assessed at population level in alignment with optimal care pathways across all stages of the cancer care continuum.MethodsData linkage performed by Centre for Victorian Data Linkage combined data from Victorian Cancer Registry with other administrative data sets including Victorian Admitted Episodes Dataset, Victorian Radiotherapy Minimum Data Set, Victorian Emergency Minimum Dataset and Victorian Death Index. A Cancer Service Performance Indicator audit was carried out providing an in‐depth analysis of identified areas of interest.ResultsOf 3138 Victorians diagnosed with pancreas ductal adenocarcinoma 2016–2019, 63% were metastatic at diagnosis. One‐year survival increased between time periods, from 29.7% overall 2011–2015 (59.1% for non‐metastatic, and 15.1% metastatic) to 32.5% overall 2016–2019 (P < 0.001), 61.2% non‐metastatic (P = 0.008), 15.7% metastatic (P = NS). A higher proportion of non‐metastatic patients progressed to surgery (35% vs. 31%, P = 0.020), and more received neoadjuvant therapy (16% vs. 4%, P < 0.001). Postoperative mortality following pancreatectomy at 30 and 90 days remained low at 2%. Utilization of 5FU‐based chemotherapy regimens increased between 2016 and 2020. Multidisciplinary Meeting (MDM) presentation was still below the 85% target (74%) as was supportive care screening (39%, target 80%).ConclusionsSurgical outcomes remain world‐class and there has been an appropriate shift in chemotherapy administration towards neoadjuvant timing with increasing use of 5FU‐based regimens. MDM presentation rates, supportive care and overall care coordination remain areas of deficiency.

Publisher

Wiley

Subject

General Medicine,Surgery

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