Muscle mass and inspired oxygen influence oxygen extraction at maximal exercise: Role of mitochondrial oxygen affinity

Author:

Cardinale D. A.12ORCID,Larsen F. J.1,Jensen-Urstad M.3,Rullman E.34,Søndergaard H.5,Morales-Alamo D.67,Ekblom B.1,Calbet J. A. L.67,Boushel R.18

Affiliation:

1. Åstrand Laboratory of Work Physiology; The Swedish School of Sport and Health Sciences; Stockholm Sweden

2. Elite Performance Centre; Bosön, Swedish Sports Confederation; Lidingö Sweden

3. Department of Cardiology; Karolinska Institute; Karolinska University Hospital; Stockholm Sweden

4. Department of Laboratory Medicine; Clinical Physiology; Karolinska Institutet; Huddinge Sweden

5. The Copenhagen Muscle Research Centre; Rigshospitalet; Copenhagen N Denmark

6. Department of Physical Education; University of Las Palmas de Gran Canaria; Las Palmas de Gran Canaria Spain

7. Research Institute of Biomedical and Health Sciences (IUIBS); Las Palmas de Gran Canaria Spain

8. School of Kinesiology; University of British Columbia; Vancouver BC Canada

Funder

Centrum for Idrottsforskning

Ministerio de Educación y Ciencia of Spain

Federación Española de Enfermedades Raras

Dr. Manuel Morales Foundation

Natural Sciences and Engineering Research Council of Canada

Publisher

Wiley

Subject

Physiology

Reference47 articles.

1. Algebraic analysis of the determinants of VO2, max;Wagner;Respir Physiol,1993

2. Point: in health and in a normoxic environment, V˙o2 max is limited primarily by cardiac output and locomotor muscle blood flow;Saltin;J Appl Physiol (1985),2006

3. Ex vivo measures of muscle mitochondrial capacity reveal quantitative limits of oxygen delivery by the circulation during exercise;Boushel;Int J Biochem Cell Biol,2013

4. Muscle mitochondrial capacity exceeds maximal oxygen delivery in humans;Boushel;Mitochondrion,2011

5. Determinants of maximal exercise VO2 during single leg knee-extensor exercise in humans;Richardson;Am J Physiol,1995

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