The ROS ‐induced cytotoxicity of ascorbate is attenuated by hypoxia and HIF ‐1alpha in the NCI 60 cancer cell lines-Reference-Cited by-同舟云学术

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The ROS ‐induced cytotoxicity of ascorbate is attenuated by hypoxia and HIF ‐1alpha in the NCI 60 cancer cell lines

Published:2013-12-14 Issue:3 Volume:18 Page:530-541
ISSN:1582-1838
Container-title:Journal of Cellular and Molecular Medicine
language:en
Short-container-title:J. Cell. Mol. Med.

Author:

Sinnberg Tobias¹,Noor Seema¹,Venturelli Sascha²,Berger Alexander²,Schuler Paul³,Garbe Claus¹,Busch Christian¹

Affiliation:

1. Division of Dermatologic Oncology Department of Dermatology and Allergology University of Tuebingen Tuebingen Germany

2. Department of Internal Medicine I Medical University Hospital Tuebingen Germany

3. Institute of Organic Chemistry University of Tuebingen Tuebingen Germany

Publisher

Wiley

Subject

Cell Biology,Molecular Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/jcmm.12207

Reference25 articles.

1. Supplemental ascorbate in the supportive treatment of cancer: Prolongation of survival times in terminal human cancer.

2. Reevaluation of Ascorbate in Cancer Treatment: Emerging Evidence, Open Minds and Serendipity

3. Pharmacologic ascorbic acid concentrations selectively kill cancer cells: Action as a pro-drug to deliver hydrogen peroxide to tissues

4. Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice

5. Mechanisms of Ascorbate-Induced Cytotoxicity in Pancreatic Cancer

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1. Analysis of High-Dose Ascorbate-Induced Cytotoxicity in Human Glioblastoma Cells and the Role of Dehydroascorbic Acid and Iron;Antioxidants;2024-09-10

2. PARP inhibition and pharmacological ascorbate demonstrate synergy in castration-resistant prostate cancer;2023-03-23

3. Oxidative Status Determines the Cytotoxicity of Ascorbic Acid in Human Oral Normal and Cancer Cells;International Journal of Molecular Sciences;2023-03-02

4. High-Dose Ascorbate in Combination with Anti-PD1 Checkpoint Inhibition as Treatment Option for Malignant Melanoma;Cells;2023-01-07

5. Prooxidant effects of high dose ascorbic acid administration on biochemical, haematological and histological changes in Cavia porcellus (Guinea pigs): a Guinea pig experimental model;Pan African Medical Journal;2023

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