Gabapentin Enacarbil Extended‐Release for Alcohol Use Disorder: A Randomized, Double‐Blind, Placebo‐Controlled, Multisite Trial Assessing Efficacy and Safety

Author:

Falk Daniel E.1ORCID,Ryan Megan L.1,Fertig Joanne B.1,Devine Eric G.2,Cruz Ricardo3,Brown E. Sherwood4ORCID,Burns Heather4,Salloum Ihsan M.5,Newport D. Jeffrey5,Mendelson John6,Galloway Gantt6,Kampman Kyle7,Brooks Catherine7,Green Alan I.8,Brunette Mary F.8,Rosenthal Richard N.910,Dunn Kelly E.11,Strain Eric C.11,Ray Lara12ORCID,Shoptaw Steven13,Ait‐Daoud Tiouririne Nassima14,Gunderson Erik W.15,Ransom Janet16,Scott Charles16,Leggio Lorenzo17ORCID,Caras Steven18,Mason Barbara J.19,Litten Raye Z.1,

Affiliation:

1. National Institute on Alcohol Abuse and Alcoholism Bethesda Maryland

2. Department of Psychiatry Boston University School of Medicine Boston Massachusetts

3. Section of General Internal Medicine Department of Medicine School of Medicine and Boston Medical Center Section of General Internal Medicine Boston University Boston Massachusetts

4. Department of Psychiatry The University of Texas Southwestern Medical Center Dallas Texas

5. Division of Alcohol and Substance Abuse Department of Psychiatry and Behavioral Sciences University of Miami Miller School of Medicine Miami Florida

6. Friends Research Institute San Francisco California

7. Department of Psychiatry Perelman School of Medicine Center for Studies of Addiction University of Pennsylvania Philadelphia Pennsylvania

8. Department of Psychiatry Geisel School of Medicine at Dartmouth Lebanon New Hampshire

9. Division of Addiction Psychiatry Stony Brook University Stony Brook New York

10. Mount Sinai St. Luke's Hospital New York New York

11. Department of Psychiatry and Behavioral Sciences Johns Hopkins University School of Medicine Baltimore Maryland

12. Department of Psychology and Department of Psychiatry and Biobehavioral Sciences University of California Los Angeles Los Angeles California

13. Department of Family Medicine and of Psychiatry and Biobehavioral Sciences David Geffen School of Medicine at UCLA, Los Angeles, California

14. Center for Leading Edge Addiction Research University of Virginia Charlottesville Virginia

15. Department of Psychiatry and Neurobehavioral Sciences and Department of Medicine University of Virginia School of Medicine Charlottesville Virginia

16. Fast Track Drugs and Biologics North Potomac Maryland

17. Section on Clinical Psychoneuroendocrinology and Neuropsychopharmacology National Institute on Alcohol Abuse and Alcoholism and National Institute on Drug Abuse National Institutes of Health Bethesda Maryland

18. Arbor Pharmaceuticals, LLC Atlanta Georgia

19. Department of Neuroscience The Scripps Research Institute La Jolla California

Funder

National Institute on Alcohol Abuse and Alcoholism

Publisher

Wiley

Subject

Psychiatry and Mental health,Toxicology,Medicine (miscellaneous)

Reference53 articles.

1. 2013 American Psychiatric Association Arlington VA American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders

2. Efficacy of a combination of flumazenil and gabapentin in the treatment of alcohol dependence: relationship to alcohol withdrawal symptoms;Anton RF;J Clin Psychopharmacol,2009

3. Gabapentin combined with naltrexone for the treatment of alcohol dependence;Anton RF;Am J Psychiatry,2011

4. Efficacy of gabapentin enacarbil vs placebo in patients with postherpetic neuralgia and a pharmacokinetic comparison with oral gabapentin;Backonja MM;Pain Med,2011

5. Gabapentin improves sleep in the presence of alcohol;Bazil CW;J Clin Sleep Med,2005

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