Diabetes distress and depression are independently associated with gastrointestinal symptoms in type 2 diabetes in Bangladesh-Reference-Cited by-同舟云学术

Diabetes distress and depression are independently associated with gastrointestinal symptoms in type 2 diabetes in Bangladesh

Published:2024-06-17 Issue: Volume: Page:
ISSN:0742-3071
Container-title:Diabetic Medicine
language:en
Short-container-title:Diabet Med

Author:

Kamruzzaman M.¹²³^ORCID,Horowitz M.¹²⁴,Polonsky W. H.⁵⁶,Talley N. J.⁷⁸,Borg M. A.⁹,Rayner C. K.¹²¹⁰^ORCID,Jones K. L.¹²⁴^ORCID,Marathe C. S.¹²⁴

Affiliation:

1. Adelaide Medical School The University of Adelaide Adelaide South Australia Australia

2. Centre of Research Excellence in Translating Nutritional Science to Good Health The University of Adelaide Adelaide South Australia Australia

3. Department of Applied Nutrition and Food Technology Islamic University Kushtia Bangladesh

4. Endocrine and Metabolic Unit Royal Adelaide Hospital Adelaide South Australia Australia

5. Behavioral Diabetes Institute San Diego California USA

6. University of California San Diego California USA

7. NHMRC Centre of Research Excellence of Digestive Health University of Newcastle Newcastle New South Wales Australia

8. Mayo Clinic Rochester Minnesota USA

9. School of Public Health The University of Adelaide Adelaide South Australia Australia

10. Department of Gastroenterology and Hepatology Royal Adelaide Hospital Adelaide South Australia Australia

Abstract

AbstractBackground and AimsGastrointestinal (GI) symptoms, common in type 2 diabetes (T2D), are typically bothersome, socially embarrassing, and impact negatively on quality of life. They may also contribute to diabetes distress (DD), but this has never been formally evaluated. We aimed to investigate the relationships between GI symptoms, DD and depressive symptoms in a large cohort of individuals with T2D in Bangladesh.Materials and Methods1406 unselected T2D individuals (female 58.8%; mean age 51.0 ± 12.5 years) from four diabetes clinics in Bangladesh completed validated questionnaires evaluating GI symptoms (PAGI‐SYM), DD (DDS‐17) and depressive symptoms (PHQ‐9).Results31.1% of participants reported GI symptoms (36.2% females, 23.7% males), while 51.1% had elevated DD and 37.8% depressive symptoms. GI symptoms exhibited independent relationships with both DD and depressive symptoms, and their likelihood was higher among those with DD (OR: 3.6 [2.2–5.6] and with depressive symptoms (OR: 5.9 [3.5–9.9]).ConclusionsGI symptoms are independently associated with both DD and depressive symptoms in people with T2D in Bangladesh.

Publisher

Wiley

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/dme.15379

Reference9 articles.

1. Gastrointestinal Symptoms in Diabetes: Prevalence, Assessment, Pathogenesis, and Management

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3. The confusing tale of depression and distress in patients with diabetes: a call for greater clarity and precision

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5. Prevalence and correlates of diabetes distress and depressive symptoms among individuals with type-2 diabetes mellitus during Ramadan fasting: A cross-sectional study in Bangladesh amid the COVID-19