Melatonin mitigates aflatoxin B1‐induced liver injury via modulation of gut microbiota/intestinal FXR/liver TLR4 signaling axis in mice-Reference-Cited by-同舟云学术

Melatonin mitigates aflatoxin B1‐induced liver injury via modulation of gut microbiota/intestinal FXR/liver TLR4 signaling axis in mice

Published:2022-06-12 Issue:2 Volume:73 Page:
ISSN:0742-3098
Container-title:Journal of Pineal Research
language:en
Short-container-title:Journal of Pineal Research

Author:

Liu Shuiping¹²³,Kang Weili¹²³,Mao Xinru¹²³,Ge Lei¹²³,Du Heng¹²³,Li Jinyan¹²³,Hou Lili¹²³,Liu Dandan¹²³,Yin Yulong⁴,Liu Yunhuan¹²³,Huang Kehe¹²³

Affiliation:

1. College of Veterinary Medicine Nanjing Agricultural University Nanjing Jiangsu China

2. Institute of Animal Nutritional Health Nanjing Agricultural University Nanjing Jiangsu China

3. MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine Nanjing Agricultural University Nanjing Jiangsu China

4. College of Animal Science and Technology Hunan Agricultural University Changsha Hunan China

Funder

National Natural Science Foundation of China

Natural Science Foundation of Jiangsu Province

Fundamental Research Funds for the Central Universities

Publisher

Wiley

Subject

Endocrinology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/jpi.12812

Reference56 articles.

1. Aflatoxin B1: A review on metabolism, toxicity, occurrence in food, occupational exposure, and detoxification methods

2. Mycotoxin exposure and human cancer risk: A systematic review of epidemiological studies

3. Critical role of caveolin-1 in aflatoxin B1-induced hepatotoxicity via the regulation of oxidation and autophagy

4. Aflatoxin B1 enhances pyroptosis of hepatocytes and activation of Kupffer cells to promote liver inflammatory injury via dephosphorylation of cyclooxygenase-2: an in vitro, ex vivo and in vivo study

5. HBx combined with AFB1 triggers hepatic steatosis via COX‐2‐mediated necrosome formation and mitochondrial dynamics disorder

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