Proteomics of colorectal cancer liver metastasis: A quantitative focus on drug elimination and pharmacodynamics effects
Author:
Affiliation:
1. Centre for Applied Pharmacokinetic Research, School of Health Sciences The University of Manchester Manchester UK
2. Translational Quantitative Pharmacology, Merck KGaA Darmstadt Germany
3. Certara Inc (Simcyp Division) Sheffield UK
Funder
Merck KGaA
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1111/bcp.15098
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4. A physiologically based pharmacokinetic (PBPK) approach to evaluate pharmacokinetics in patients with cancer;Cheeti S;Biopharm Drug Dispos,2013
5. Significantly Decreased and More Variable Expression of Major CYPs and UGTs in Liver Microsomes Prepared from HBV‐Positive Human Hepatocellular Carcinoma and Matched Pericarcinomatous Tissues Determined Using an Isotope Label‐free UPLC‐MS/MS Method;Yan T;Pharm Res,2015
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