Opioids and personalized analgesia in the perioperative setting: A protocol for five systematic reviews-Reference-Cited by-同舟云学术

Opioids and personalized analgesia in the perioperative setting: A protocol for five systematic reviews

Published:2024-08-06 Issue: Volume: Page:
ISSN:0001-5172
Container-title:Acta Anaesthesiologica Scandinavica
language:en
Short-container-title:Acta Anaesthesiol Scand

Author:

Karlsen Anders Peder Højer¹^ORCID,Sunde Pernille Bjersand¹^ORCID,Olsen Markus Harboe²³⁴^ORCID,Laigaard Jens⁵^ORCID,Folkersen Caroline¹²,Tran Trang Xuan Minh¹^ORCID,Rasmussen Ida Houtved¹²,Kjartansdóttir Selma¹⁶^ORCID,Saito Atena⁷^ORCID,Andersen Michael Asger⁶^ORCID,Maagaard Mathias²^ORCID,Papadomanolakis‐Pakis Nicholas⁸^ORCID,Dalhoff Kim⁶⁹^ORCID,Nikolajsen Lone⁸^ORCID,Lunn Troels Haxholdt¹⁸,Meyhoff Christian Sylvest¹⁹^ORCID,Jakobsen Janus Christian³¹⁰^ORCID,Mathiesen Ole²⁹^ORCID

Affiliation:

1. Department of Anaesthesia and Intensive Care Copenhagen University Hospital – Bispebjerg and Frederiksberg Copenhagen Denmark

2. Centre for Anaesthesiological Research, Department of Anaesthesiology Zealand University Hospital Roskilde Denmark

3. Copenhagen Trial Unit, Centre for Clinical Intervention Research, The Capital Region Copenhagen University Hospital – Rigshospitalet Copenhagen Denmark

4. Department of Neuroanaesthesiology, Neuroscience Centre Copenhagen University Hospital – Rigshospitalet Copenhagen Denmark

5. Department of Orthopedic surgery Bispebjerg and Frederiksberg Hospital Copenhagen Denmark

6. Department of Clinical Pharmacology Copenhagen University Hospital – Bispebjerg and Frederiksberg Copenhagen Denmark

7. Pontifical Catholic University of Campinas Sao Paulo Brazil

8. Department of Anaesthesia and Intensive Care Aarhus University Hospital Aarhus Denmark

9. Department of Clinical Medicine University of Copenhagen Copenhagen Denmark

10. Department of Regional Health Research, The Faculty of Health Sciences University of Southern Denmark Odense Denmark

Abstract

AbstractBackgroundTreatment with opioids is a mainstay in perioperative pain management. While the leading treatment paradigm has been procedure‐specific pain management, efforts regarding personalized pain treatment are increasing. The OPI•AID project aims to develop personalized algorithms for perioperative pain management, taking demographic, surgical, and anaesthesiologic factors into account. We will undertake five parallel reviews to illuminate current evidence on different aspects of individual responses to perioperative opioid treatment.MethodsInclusion of adult populations in English‐written studies. Review‐specific searches are developed for the following databases: CENTRAL, MEDLINE, Embase, clinicaltrials.gov, and clinicaltrial.eu. Two authors will independently screen citations, extract data, and assess the risks of bias in each review (QUIPS, PROBAST and RoB2, as relevant).ConclusionThese reviews will evaluate various aspects of perioperative opioid treatment, including individualized treatment strategies, selection of specific opioids, and individual patient responses. These will guide future development of a personalized perioperative opioid treatment algorithm (OPI•AID) that will be validated and tested clinically against standard of care.

Publisher

Wiley

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/aas.14508

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