Allosterism-based simultaneous, dual anticoagulant and antiplatelet action: allosteric inhibitor targeting the glycoprotein Ibα-binding and heparin-binding site of thrombin-Reference-Cited by-同舟云学术

Allosterism-based simultaneous, dual anticoagulant and antiplatelet action: allosteric inhibitor targeting the glycoprotein Ibα-binding and heparin-binding site of thrombin

Published:2016-02-16 Issue:4 Volume:14 Page:828-838
ISSN:1538-7933
Container-title:Journal of Thrombosis and Haemostasis
language:en
Short-container-title:J Thromb Haemost

Author:

Mehta A. Y.¹,Mohammed B. M.²³,Martin E. J.²,Brophy D. F.²,Gailani D.⁴,Desai U. R.¹

Affiliation:

1. Department of Medicinal Chemistry and Institute for Structural Biology; Drug Discovery and Development; Virginia Commonwealth University; Richmond VA USA

2. Department of Pharmacotherapy and Outcomes Science; Virginia Commonwealth University; Richmond VA USA

3. Department of Clinical Pharmacy; Faculty of Pharmacy; Cairo University; Cairo Egypt

4. Department of Pathology, Immunology and Microbiology; Vanderbilt University Medical Center; Nashville TN USA

Funder

National Institutes of Health

Publisher

Wiley

Subject

Hematology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/jth.13254/fullpdf

Reference59 articles.

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2. Prevention of venous thromboembolism: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition);Geerts;Chest,2008

3. Antithrombotic therapy for venous thromboembolic disease: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition);Kearon;Chest,2008

4. Meta-analysis: low-molecular-weight heparin and bleeding in patients with severe renal insufficiency;Lim;Ann Intern Med,2006

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