A pilot study on the efficacy of a seaweed mud application in the treatment of cellulite

Author:

Amuso Domenico1,Medoro Alessandro2ORCID,Scapagnini Giovanni2ORCID,Gambacorta Angela3,Davinelli Sergio2ORCID,Iorio Eugenio Luigi4ORCID,Bonetti Luca Reggiani5ORCID,Sbarbati Andrea6

Affiliation:

1. Department of Innovative Technologies in Medicine and Dentistry University of Chieti‐Pescara Chieti Italy

2. Department of Medicine and Health Sciences “V. Tiberio” University of Molise Campobasso Italy

3. USL Umbria 1 Perugia Italy

4. Campus Uberlândia Universidade de Uberaba (UNIUBE) Uberlândia Brazil

5. Department of Medical and Surgical Sciences for Children & Adults, Division of Pathology University‐Hospital of Modena and Reggio Emilia Modena Italy

6. Department of Neurosciences, Biomedicine and Movement Sciences, Anatomy and Histology Section, School of Medicine University of Verona Verona Italy

Abstract

AbstractBackgroundCellulite represents a common multi‐factorial condition that affects nearly all women and is now recognized as a clinical condition associated with systemic factors and negative psychological effects. Several noninvasive and minimally invasive treatments were developed during the last few years, but limited evidence supports many of them due to lack of evidence, insufficient participants, and potential adverse effects.MethodsThis study aimed to evaluate the efficacy of a seaweed mud application in improving both the structure and function of tissues affected by cellulite. Sixty women with cellulite underwent 4‐week applications of seaweed mud on the buttocks and thighs. The following assessments were performed at baseline and after the last treatment: photographic, clinical, and anthropometric evaluation; tests for elasticity and hydration; ultrasonography of cellulite nodules; and cellulite biopsies in the trochanteric region. Patient satisfaction was assessed using a 5‐point Likert‐scale questionnaire.ResultsThe treatment resulted in a significant improvement in the severity of cellulite severity between the initial assessment and the 4‐week follow‐up, with enhanced structure, elasticity, and hydration of the affected tissues. Microscopic analysis of the cellulite biopsies revealed a significant restoration of dermal organization with induced collagen synthesis and reduced inflammation, edema, and lipid deposition following the 4‐week seaweed mud applications. Additionally, the treatment led to a remarkable improvement in comfort and satisfaction as well as a reduction in body circumferences.ConclusionsThe cosmetic application of seaweed mud has proven to be a safe, non‐invasive treatment for improving the tissue alterations characteristic of cellulite.

Publisher

Wiley

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