Apremilast for moderate hidradenitis suppurativa: no significant change in lesional skin inflammatory biomarkers
Author:
Affiliation:
1. Department of Dermatology Erasmus University Medical Center Rotterdam The Netherlands
2. Laboratory of Rheumatology & Dermatology Erasmus University Medical Center Rotterdam The Netherlands
Funder
AbbVie
Celgene
Novartis
Pfizer
Amgen
Biogen
UCB
Publisher
Wiley
Subject
Infectious Diseases,Dermatology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1111/jdv.15354
Reference17 articles.
1. Hidradenitis suppurativa/acne inversa: a practical framework for treatment optimization – systematic review and recommendations from the HS ALLIANCE working group
2. Apremilast for moderate hidradenitis suppurativa: results of a randomized controlled trial;Vossen ARJV;J Am Acad Dermatol,2018
3. IL-1? and IFN-? induce the regenerative epidermal phenotype of psoriasis in the transwell skin organ culture system. IFN-? up-regulates the expression of keratin 17 and keratinocyte transglutaminase via endogenous IL-1 production
4. A modified ex vivo skin organ culture system for functional studies
5. An improvement of the 2^(‐delta delta CT) method for quantitative real‐time polymerase chain reaction data analysis;Rao X;Biostat Bioinforma Biomath,2013
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1. Orismilast for the treatment of mild to severe hidradenitis suppurativa: Week 16 data from OSIRIS, a Phase 2a, open‐label, single‐centre, single‐arm, dose‐finding clinical trial;Journal of the European Academy of Dermatology and Venereology;2023-12-26
2. Orismilast in moderate-to-severe psoriasis: Efficacy and safety from a 16-week, randomized, double-blinded, placebo-controlled, dose-finding, and phase 2b trial (IASOS);Journal of the American Academy of Dermatology;2023-11
3. Guselkumab for hidradenitis suppurativa: a phase II, open-label, mode-of-action study;British Journal of Dermatology;2023-02-22
4. HS 3D-SeboSkin Model Enables the Preclinical Exploration of Therapeutic Candidates for Hidradenitis Suppurativa/Acne Inversa;Pharmaceutics;2023-02-12
5. Evolving utility of apremilast in dermatological disorders for off-label indications;Clinical and Experimental Dermatology;2022-12-01
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