Vaccines and allergy: Back to the right places

Author:

Moschese Viviana1ORCID,Montin Davide2,Ottaviano Giorgio3,Sgrulletti Mayla14ORCID,Beni Alessandra5ORCID,Costagliola Giorgio6,Sangerardi Maria7,Santilli Veronica8,Miraglia Del Giudice Michele9,Rizzo Caterina10,Martire Baldassarre11,

Affiliation:

1. Pediatric Immunopathology and Allergology Unit, Policlinico Tor Vergata University of Rome Tor Vergata Rome Italy

2. Division of Pediatric Immunology and Rheumatology, Department of Public Health and Pediatrics “Regina Margherita” Children Hospital, University of Turin Turin Italy

3. Department of Pediatrics Fondazione IRCCS San Gerardo Dei Tintori Monza Italy

4. PhD Program in Immunology, Molecular Medicine and Applied Biotechnology University of Rome Tor Vergata Rome Italy

5. Department of Clinical and Experimental Medicine University of Pisa Pisa Italy

6. Section of Pediatric Hematology and Oncology Azienda Ospedaliero Universitaria Pisana Pisa Italy

7. Department of Pediatrics and Emergency Azienda Ospedaliero Universitaria Consorziale Policlinico, Ospedale Pediatrico Giovanni XXIII Bari Italy

8. Academic Department of Pediatrics (DPUO), Research Unit of Clinical Immunology and Vaccinology IRCCS Bambino Gesù Children's Hospital Rome Italy

9. Department of Woman, Child and General and Specialized Surgery University of Campania “Luigi Vanvitelli” Naples Italy

10. Department of Translational Research and New Technologies in Medicine and Surgery University of Pisa Pisa Italy

11. UOC of Pediatrics and Neonatology “Monsignor A.R. Dimiccoli” Hospital Barletta Italy

Abstract

AbstractHypersensitivity reactions represent one of the most common causes of hesitancy for adherence to national vaccination programs. The majority of hypersensitivity reactions after vaccination are mild, and anaphylaxis is reported to be rare, although it remains challenging to estimate the frequency attributed to each single vaccine, either because of the lower number of administered doses of less common vaccines, or the administration of simultaneous vaccine in most of the vaccination programs. Although literature remains scattered, international consensus guides clinicians in identifying patients who might need the administration of vaccines in protected environments due to demonstrated hypersensitivity to vaccine components or adjuvants. Here we provide the current guidance on hypersensitivity reactions to vaccines and on vaccination of children with allergy disorders.

Publisher

Wiley

Reference114 articles.

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