Safety, tolerability, and pharmacokinetics of radavirsen (AVI-7100), an antisense oligonucleotide targeting influenza a M1/M2 translation-Reference-Cited by-同舟云学术

Safety, tolerability, and pharmacokinetics of radavirsen (AVI-7100), an antisense oligonucleotide targeting influenza a M1/M2 translation

Published:2017-09-22 Issue:1 Volume:84 Page:25-34
ISSN:0306-5251
Container-title:British Journal of Clinical Pharmacology
language:en
Short-container-title:Br J Clin Pharmacol

Author:

Beigel John H.¹^ORCID,Voell Jocelyn²,Muñoz Paula²,Kumar Parag³,Brooks Kristina M.³,Zhang Jianbo⁴,Iversen Patrick⁴,Heald Alison⁴,Wong Michael⁴,Davey Richard T.²

Affiliation:

1. Leidos Biomedical Research; Frederick MD USA

2. National Institute of Allergy and Infectious Diseases; National Institutes of Health; Bethesda MD USA

3. National Institutes of Health Clinical Center; National Institutes of Health; Bethesda MD USA

4. Sarepta Therapeutics; Cambridge MA USA

Funder

Division of Intramural Research, National Institute of Allergy and Infectious Diseases

Intramural Research Programs of the National Institute of Allergy and Infectious Diseases and Clinical Center, National Institutes of Health

National Cancer Institute, National Institutes of Health

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/bcp.13405/fullpdf

Reference11 articles.

1. A new class of antivirals: antisense oligonucleotides combined with a hydrophobic substituent effectively inhibit influenza virus reproduction and synthesis of virus-specific proteins in MDCK cells;Kabanov;FEBS Lett,1990

2. Oligodeoxynucleotide hybridization inhibition of HIV and influenza virus;Zamecnik;Nucleic Acids Symp Ser,1991

3. Inhibitory effects of an antisense oligonucleotide in an experimentally infected mouse model of influenza a virus;Mizuta;Biochem Biophys Res Commun,2000

4. Inhibition of influenza virus production in virus-infected mice by RNA interference;Ge;Proc Natl Acad Sci U S A,2004

5. Morpholino oligomers targeting the PB1 and NP genes enhance the survival of mice infected with highly pathogenic influenza a H7N7 virus;Gabriel;J Gen Virol,2008

Cited by 16 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Antiviral Efficacy of RNase H-Dependent Gapmer Antisense Oligonucleotides against Japanese Encephalitis Virus;International Journal of Molecular Sciences;2023-10-02

2. Antisense oligonucleotides: a promising therapeutic option against infectious diseases;Nucleosides, Nucleotides & Nucleic Acids;2023-07-03

3. Antiviral Approaches against Influenza Virus;Clinical Microbiology Reviews;2023-03-23

4. The convergent evolution of influenza A virus: Implications, therapeutic strategies and what we need to know;Current Research in Microbial Sciences;2023

5. Inhaled siRNA Formulations for Respiratory Diseases: From Basic Research to Clinical Application;Pharmaceutics;2022-06-02