Affiliation:
1. Department of Haematology Whittington Health London UK
2. Department of Haematology University Hospitals Coventry and Warwickshire Coventry UK
3. Department of Haematology Leicester Royal infirmary Leicester UK
4. Department of Haematology Sandwell and West Birmingham NHS Trust West Bromwich UK
5. Department of Obstetrics and Gynaecology Whittington Health London UK
6. Department of Endocrinology Whittington Health London UK
Abstract
SummaryThis comprehensive guideline, developed by a representative group of UK‐based medical experts specialising in haemoglobinopathies, addresses the management of conception and pregnancy in patients with thalassaemia. A systematic search of PubMed and EMBASE using specific keywords, formed the basis of the literature review. Key terms included “thalassaemia,” “pregnancy,” “Cooley's anaemia,” “Mediterranean anaemia,” and others, covering aspects such as fertility, iron burden and ultrasonography. The guideline underwent rigorous review by prominent organisations, including the Endocrine Society, the Royal College of Obstetricians and Gynaecologists (RCOG), the United Kingdom Thalassaemia Society and the British Society of Haematology (BSH) guideline writing group. Additional feedback was solicited from a sounding board of UK haematologists, ensuring a thorough and collaborative approach. The objective of the guideline is to equip healthcare professionals with precise recommendations for managing conception and pregnancy in patients with thalassaemia.