Celastrol induces proteasomal degradation of FANCD 2 to sensitize lung cancer cells to DNA crosslinking agents

Author:

Wang Gui‐Zhen12,Liu Yong‐Qiang1,Cheng Xin1,Zhou Guang‐Biao1

Affiliation:

1. Division of Molecular Carcinogenesis and Targeted Therapy for Cancer State Key Laboratory of Biomembrane and Membrane Biotechnology Institute of Zoology Chinese Academy of Sciences BeijingChina

2. University of Chinese Academy of Sciences Beijing China

Funder

National Natural Science Foundation of China

The National Natural Science Funds of China for Distinguished Young Scholar

Publisher

Wiley

Subject

Cancer Research,Oncology,General Medicine

Reference46 articles.

1. World Health Organization.GLOBOCAN 2012. GLOBOCAN 2013. [Cited 24 Dec 2014.] Available from URL:http://globocaniarcfr/Pages/fact_sheets_canceraspx.

2. Global cancer statistics

3. Lung Cancer

4. Platinum drugs and DNA repair mechanisms in lung cancer;Bonanno L;Anticancer Res,2014

5. Molecular mechanisms of cisplatin resistance

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