Double knockout pigs deficient in N-glycolylneuraminic acid and Galactose α-1,3-Galactose reduce the humoral barrier to xenotransplantation-Reference-Cited by-同舟云学术

Double knockout pigs deficient in N-glycolylneuraminic acid and Galactose α-1,3-Galactose reduce the humoral barrier to xenotransplantation

Published:2013-01 Issue:1 Volume:20 Page:27-35
ISSN:0908-665X
Container-title:Xenotransplantation
language:en
Short-container-title:

Author:

Lutz Andrew J.¹,Li Ping¹,Estrada Jose L.¹,Sidner Richard A.¹,Chihara Ray K.¹,Downey Susan M.¹,Burlak Christopher¹,Wang Zheng-Yu¹,Reyes Luz M.¹,Ivary Bess¹,Yin Fuqin¹,Blankenship Ross L.¹,Paris Leela L.¹,Tector A. Joseph¹

Affiliation:

1. Department of Surgery; Transplant; Indiana University School of Medicine; Indianapolis; IN; USA

Publisher

Wiley

Subject

Transplantation,Immunology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/xen.12019/fullpdf

Reference17 articles.

1. Production of alpha 1,3-galactosyltransferase-deficient pigs;Phelps;Science,2002

2. Production of alpha-1,3-galactosyltransferase null pigs by means of nuclear transfer with fibroblasts bearing loss of heterozygosity mutations;Kolber-Simonds;Proc Natl Acad Sci U S A,2004

3. Acute rejection is associated with antibodies to non-Gal antigens in baboons using Gal-knockout pig kidneys;Chen;Nat Med,2005

4. Cloning and functional characterization of pig CMP-N-acetylneuraminic acid hydroxylase for the synthesis of N-glycolylneuraminic acid as the xenoantigenic determinant in pig-human xenotransplantation;Song;Biochem J,2010

5. Loss of N-glycolylneuraminic acid in humans: mechanisms, consequences, and implications for hominid evolution;Varki;Yearb Phys Anthropol,2001

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