Targeting mTOR for the treatment of B cell malignancies-Reference-Cited by-同舟云学术

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Targeting mTOR for the treatment of B cell malignancies

Published:2016-03-03 Issue:5 Volume:82 Page:1213-1228
ISSN:0306-5251
Container-title:British Journal of Clinical Pharmacology
language:en
Short-container-title:Br J Clin Pharmacol

Author:

Lee Jong-Hoon Scott¹,Vo Thanh-Trang¹,Fruman David A.¹

Affiliation:

1. Department of Molecular Biology & Biochemistry; University of California; Irvine, USA

Funder

Kirschstein National Research Service Award from the National Institutes of Health

National Institutes of Health

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/bcp.12888/fullpdf

Reference175 articles.

1. mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery;Kim;Cell,2002

2. Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton;Sarbassov;Curr Biol,2004

3. PtdIns(3,4,5)P3-dependent activation of the mTORC2 kinase complex;Liu;Cancer Discov,2015

4. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex;Sarbassov;Science,2005

5. PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond;Marte;Trends Biochem Sci,1997

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