Sublingual administration improves systemic exposure of tacrolimus in kidney transplant recipients: comparison with oral administration

Author:

Federico Stefano1,Carrano Rosa1,Sabbatini Massimo1,Nappi Riccardo1,Russo Luigi1,Apicella Luca1,Balletta Mario Maria1,Santangelo Michele2,Mosca Teresa3,Tarantino Giovanni4,Capone Domenico3

Affiliation:

1. Department of Public Health; Section of Nephrology and Renal Transplantation; “Federico II” University; Naples Italy

2. Department of Advanced Biomedical Sciences; Operative Unit of General Surgery and Transplantation; “Federico II” University; Naples Italy

3. Integrated Care Department of Clinical Neurosciences, Anestesiology and Drug-Use; Section of Clinical Pharmacology; “Federico II” University; Naples Italy

4. Department of Clinical Medicine and Surgery; “Federico II” University; Naples Italy

Publisher

Wiley

Subject

Clinical Biochemistry,Biochemistry,General Medicine

Reference29 articles.

1. Prograf_ FDA Technical Data of Tacrolimus http://www.rxlist.com/prograf-drug.htm

2. Clinical pharmacology of immunosuppressive drugs: year 2000-time for alternative;Billaud;Therapie,2000

3. Immunosuppressive drugs for kidney transplantation;Halloran;N Engl J Med,2004

4. Population pharmacokinetics and bioavailability of tacrolimus in kidney transplant patients;Antignac;Br J Clin Pharmacol,2007

5. Intravenous cyclosporine and tacrolimus caused anaphylaxis but oral cyclosporine capsules were tolerated in an allogenic bone marrow transplant recipient;Takamatsu;Bone Marrow Transplant,2001

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