p16INK4a-induced senescence is disabled by melanoma-associated mutations

Author:

Haferkamp Sebastian,Becker Therese M.,Scurr Lyndee L.,Kefford Richard F.,Rizos Helen

Publisher

Wiley

Subject

Cell Biology,Aging

Reference64 articles.

1. Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts;Alcorta;Proc. Natl Acad. Sci. USA,1996

2. G1 arrest by p16 (INK4A) uncouples growth from cell cycle progression in leukemia cells with deregulated cyclin E and c-Myc expression;Ausserlechner;Leukemia,2005

3. Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints;Bartkova;Nature,2006

4. Reversal of human cellular senescence: roles of the p53 and p16 pathways;Beausejour;EMBO J,2003

5. Functional impairment of melanoma-associated p16INK4a mutants in melanoma cells despite retention of cyclin-dependent kinase 4 binding;Becker;Clin. Cancer Res,2001

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