Lifelong rapamycin administration ameliorates age-dependent cognitive deficits by reducing IL-1β and enhancing NMDA signaling
Author:
Publisher
Wiley
Subject
Cell Biology,Aging
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1474-9726.2011.00791.x/fullpdf
Reference45 articles.
1. Interleukin-1 and neuronal injury;Allan;Nat. Rev. Immunol.,2005
2. Time course of hippocampal IL-1 beta and memory consolidation impairments in aging rats following peripheral infection;Barrientos;Brain Behav. Immun.,2009
3. Rapamycin alleviates toxicity of different aggregate-prone proteins;Berger;Hum. Mol. Genet.,2006
4. Excess protein synthesis in Drosophila fragile X mutants impairs long-term memory;Bolduc;Nat. Neurosci.,2008
5. Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments;Caccamo;J. Biol. Chem.,2010a
Cited by 181 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Effect and Mechanism of Rapamycin on Cognitive Deficits in Animal Models of Alzheimer’s Disease: A Systematic Review and Meta-analysis of Preclinical Studies;Journal of Alzheimer's Disease;2024-04-30
2. Seizures exacerbate excitatory: inhibitory imbalance in Alzheimer’s disease and 5XFAD mice;Brain;2024-04-25
3. Inhibition of S6K lowers age-related inflammation and increases lifespan through the endolysosomal system;Nature Aging;2024-02-27
4. mTOR signaling and Alzheimer's disease: What we know and where we are?;CNS Neuroscience & Therapeutics;2023-09-18
5. Ageing-associated phenotypes in mice;Mechanisms of Ageing and Development;2023-09
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3