Evidence that the pregnane X and retinoid receptors PXR, RAR and RXR may regulate transcription of the transporterhOCT1in chronic myeloid leukaemia cells
Author:
Affiliation:
1. Section of Haematology; Department of Molecular and Clinical Cancer Medicine; University of Liverpool; Liverpool UK
Publisher
Wiley
Subject
Hematology,General Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/ejh.12409/fullpdf
Reference19 articles.
1. A population study showing that the advent of second generation tyrosine kinase inhibitors has improved progression-free survival in chronic myeloid leukaemia;Francis;Leuk Res,2013
2. EVI-1 oncogene expression predicts survival in chronic-phase CML patients resistant to imatinib treated with second-generation tyrosine kinase inhibitors;Daghistani;Blood,2010
3. Expression of the uptake drug transporter hOCT1 is an important clinical determinant of the response to imatinib in chronic myeloid leukemia;Wang;Clin Pharmacol Ther,2008
4. Most CML patients who have a suboptimal response to imatinib have low OCT-1 activity: higher doses of imatinib may overcome the negative impact of low OCT-1 activity;White;Blood,2007
5. Genomic analysis of the nuclear receptor family: new insights into structure, regulation, and evolution from the rat genome;Zhang;Genome Res,2004
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