Anti-ictogenic and antiepileptogenic properties of perampanel in mature and immature rats

Author:

Dupuis Nina12,Enderlin Julie12,Thomas Jeremy3,Desnous Béatrice124,Dournaud Pascal12,Allorge Delphine3,Auvin Stéphane124ORCID

Affiliation:

1. National Institute of Health and Medical Research, U1141; Paris France

2. Sorbonne Paris Cité; Paris Diderot University; National Institute of Health and Medical Research UMR1141; Paris France

3. Functional Toxicology Unit, Lille University Hospital Center; Lille France

4. Pediatric Neurology Department; Robert Debré Hospital; Public Hospital Network of Paris; Paris France

Funder

Eisai

Publisher

Wiley

Subject

Clinical Neurology,Neurology

Reference31 articles.

1. Revisiting AMPA receptors as an antiepileptic drug target;Rogawski;Epilepsy Curr,2011

2. The anticonvulsant effect of the non-NMDA antagonists, NBQX and GYKI 52466, in mice;Chapman;Epilepsy Res,1991

3. Effects of the non-NMDA antagonists NBQX and the 2,3-benzodiazepine GYKI 52466 on different seizure types in mice: comparison with diazepam and interactions with flumazenil;Loscher;Br J Pharmacol,1994

4. Low doses of NMDA receptor antagonists synergistically increase the anticonvulsant effect of the AMPA receptor antagonist NBQX in the kindling model of epilepsy;Loscher;Eur J Neurosci,1993

5. Relief of experimental spasticity and anxiolytic/anticonvulsant actions of the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate antagonist 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline;Turski;J Pharmacol Exp Ther,1992

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