Safety, pharmacokinetics and pharmacodynamics of branebrutinib (BMS‐986195), a covalent, irreversible inhibitor of Bruton's tyrosine kinase: Randomised phase I, placebo‐controlled trial in healthy participants
Author:
Affiliation:
1. Bristol Myers Squibb Princeton NJ USA
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1111/bcp.14290
Reference30 articles.
1. Tec family of protein-tyrosine kinases: an overview of their structure and function
2. Expression of Bruton's agammaglobulinemia tyrosine kinase gene, BTK, is selectively down‐regulated in T lymphocytes and plasma cells;Smith CI;J Immunol,1994
3. The role of Bruton's tyrosine kinase in B-cell development and function: a genetic perspective
4. Specific Btk inhibition suppresses B cell– and myeloid cell–mediated arthritis
5. Enhanced Bruton's Tyrosine Kinase Activity in Peripheral Blood B Lymphocytes From Patients With Autoimmune Disease
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