Synthesis and Antimicrobial Activity of the Hybrid Molecules between Sulfonamides and Active Antimicrobial Pleuromutilin Derivative

Author:

Chen Liangzhu12,Yang Dexue2,Pan Zhikun1,Lai Lihong2,Liu Jianhua2,Fang Binghu12,Shi Shuning2

Affiliation:

1. Guangdong Dahuanong Animal Health Products Co. Ltd.; Yunfu 527400 China

2. Department of Veterinary Medicine; South China Agricultural University; Guangzhou 510642 China

Funder

National Science Foundation of China

Program for Changjiang Scholars and Innovative Research Team in University

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Reference17 articles.

1. Positive clinical risk factors predict a high rate of methicillin-resistant Staphylococcus aureus colonization in emergency department patients;Wakatake;Am J Infect Control,2012

2. First isolation and detection of multiple clones of vancomycin-resistant enterococci in the pediatric unit of Van Yuzuncu Yil university, Turkey;Guducuoglu;Mikrobiyol Bul,2009

3. Antibiotic substance from basidiomycetes: VIII. pleurotus mutilus (Fr.) Sacc. and Pleurotus passeckerianus Pilat;Kavanagh;Proc Natl Acad Sci USA,1951

4. Chemical studies with pleuromutilin;Anchel;J Biol Chem,1952

5. Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity;Davidovich;Proc Natl Acad Sci USA,2007

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