Targeted deletion of the antisilencer/enhancer (ASE) element from intron 1 of the myelin proteolipid protein gene (Plp1 ) in mouse reveals that the element is dispensable for Plp1 expression in brain during development and remyelination
Author:
Affiliation:
1. Department of Physiology and Biophysics; University of Arkansas for Medical Sciences; Little Rock Arkansas USA
2. Department of Obstetrics and Gynecology; University of Iowa; Iowa City Iowa USA
Funder
National Multiple Sclerosis Society
NIH
UAMS College of Medicine Research Council
Publisher
Wiley
Subject
Cellular and Molecular Neuroscience,Biochemistry
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/jnc.12092/fullpdf
Reference47 articles.
1. Genetic analysis of a conserved sequence in the HoxD complex: regulatory redundancy or limitations of the transgenic approach?;Beckers;Dev. Dyn.,1998
2. The core enhancer is essential for proper timing of MyoD activation in limb buds and branchial arches;Chen;Dev. Biol.,2004
3. Essential and redundant functions of the MyoD distal regulatory region revealed by targeted mutagenesis;Chen;Dev. Biol.,2002
4. Antisilencing: myelin proteolipid protein gene expression in oligodendrocytes is regulated via derepression;Dobretsova;J. Neurochem.,1999
5. Functional characterization of cis-acting DNA antisilencer region that modulates myelin proteolipid protein gene expression;Dobretsova;J. Neurochem.,2000
Cited by 6 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Plp1 in the enteric nervous system is preferentially expressed during early postnatal development in mouse as DM20, whose expression appears reliant on an intronic enhancer;Frontiers in Cellular Neuroscience;2023-05-24
2. PLP1-lacZ transgenic mice reveal that splice variants containing “human-specific” exons are relatively minor in comparison to the archetypal transcript and that an upstream regulatory element bolsters expression during early postnatal brain development;Frontiers in Cellular Neuroscience;2023-01-11
3. Identifying oligodendrocyte enhancers governing Plp1 expression;Human Molecular Genetics;2021-07-06
4. The wmN1 Enhancer Region of the Mouse Myelin Proteolipid Protein Gene (mPlp1) is Indispensable for Expression of an mPlp1-lacZ Transgene in Both the CNS and PNS;Neurochemical Research;2019-11-28
5. The wmN1 enhancer region in intron 1 is required for expression of humanPLP1;Glia;2018-04-23
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3