Epidemiology of in‐hospital cardiac arrest patients admitted to the intensive care unit in Australia: a retrospective observational study

Author:

Veerappa Shilpa1,Orosz Judit1,Bailey Michael2,Pilcher David34567ORCID,Jones Daryl8910ORCID

Affiliation:

1. Intensive Care and Hyperbaric Services Alfred Health Melbourne Victoria Australia

2. Australian and New Zealand Intensive Care Research Centre, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine Monash University Melbourne Victoria Australia

3. Department of Intensive Care Alfred Health Melbourne Victoria Australia

4. The Australian and New Zealand Intensive Care Society (ANZICS) Centre for Outcome and Resources Evaluation Melbourne Victoria Australia

5. The Australian and New Zealand Intensive Care – Research Centre, School of Public Health and Preventive Medicine Monash University Melbourne Victoria Australia

6. Critical Care Network Safer Care Victoria Melbourne Victoria Australia

7. Donate Life in Victoria Melbourne Victoria Australia

8. Austin Health Melbourne Victoria Australia

9. Department of Epidemiology and Preventive Medicine Monash University Melbourne Victoria Australia

10. Australian and New Zealand Intensive Care Research Centre (ANZIC‐RC) Melbourne Victoria Australia

Abstract

AbstractBackgroundIn‐hospital cardiac arrest (IHCA) affects approximately 3000 patients annually in Australia. Introduction of the National Standard for Deteriorating Patients in 2011 was associated with reduced IHCA‐related intensive care unit (ICU) admissions and reduced in‐hospital mortality of such patients.AimsTo assess whether the reduction in IHCA‐related ICU admissions from hospital wards seen following the implementation of the national standard (baseline period 2013–2014) was sustained over the follow‐up period (2015–2019) in Australia.MethodsA multi‐centre retrospective cohort study to compare the characteristics and outcomes of IHCA admitted to the ICU between baseline and follow‐up periods. The primary outcome was the proportion of patients admitted to ICU from the ward following IHCA. Secondary outcomes included ICU and hospital mortality of IHCA‐related ICU admissions. Data were analysed using hierarchical multivariable logistic regression.ResultsThe proportion of cardiac arrest‐related admissions from the ward was lower in the follow‐up period when compared to baseline (4.1 vs 3.8%; P = 0.04). Such patients had lower illness severity and were more likely to have limitations of medical treatment at admission. However, after adjustment for severity of illness, the likelihood of being admitted to ICU following cardiac arrest on the ward increased in the follow‐up period (odds ratio (OR) 1.13 (1.05–1.22); P = 0.001). Hospital mortality was lower in the follow‐up period (50.3 vs 46.3%; P = 0.02), but after adjustment the likelihood of death did not differ between the periods (OR 1.0 (0.86–1.17); P = 0.98).ConclusionAfter adjustment for the severity of illness, the likelihood of being admitted to ICU after IHCA slightly increased in the follow‐up period.

Publisher

Wiley

Subject

Internal Medicine

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