Bcl‐x L as prognostic marker and potential therapeutic target in cholangiocarcinoma

Author:

Hoffmeister‐Wittmann Paula12ORCID,Mock Andreas1345,Nichetti Federico67,Korell Felix48,Heilig Christoph E.34,Scherr Anna‐Lena1,Günther Michael45,Albrecht Thomas910ORCID,Kelmendi Eblina1,Xu Kaiyu1,Nader Luisa1,Kessler Annika1,Schmitt Nathalie1,Fritzsche Sarah910,Weiler Sofia910,Sobol Benjamin1,Stenzinger Albrecht9,Boeck Stefan411,Westphalen Christoph B.411,Schulze‐Osthoff Klaus412,Trojan Jörg413,Kindler Thomas414,Weichert Wilko415,Spiekermann Karsten3416,Bitzer Michael417,Folprecht Gunnar418,Illert Anna L.41920,Boerries Melanie42021,Klauschen Frederick422,Ochsenreither Sebastian42324,Siveke Jens42526,Bauer Sebastian427,Glimm Hanno28293031,Brors Benedikt7,Hüllein Jennifer7,Hübschmann Daniel4732,Uhrig Sebastian7,Horak Peter34,Kreutzfeldt Simon34,Banales Jesus M.3334ORCID,Springfeld Christoph1,Jäger Dirk1,Schirmacher Peter910,Roessler Stephanie910ORCID,Ormanns Steffen45,Goeppert Benjamin91035ORCID,Fröhling Stefan34,Köhler Bruno C.1410ORCID

Affiliation:

1. Department of Medical Oncology, National Center for Tumor Diseases (NCT) Heidelberg University Hospital Heidelberg Heidelberg Germany

2. Department of Radiooncology University Hospital Heidelberg Heidelberg Germany

3. Department of Translational Medical Oncology NCT Heidelberg and German Cancer Research Center (DKFZ) Heidelberg Germany

4. German Cancer Consortium (DKTK), Heidelberg and Partner Sites Heidelberg Germany

5. Institute of Pathology, Medical Faculty Ludwig‐Maximilians‐University Munich Germany

6. Department of Medical Oncology Fondazione IRCCS Istituto Nazionale Dei Tumori Milan Italy

7. Computational Oncology Group, Molecular Precision Oncology Program, National Center for Tumor Diseases (NCT) and German Cancer Research Center (DKFZ) Heidelberg Germany

8. Department of Medicine V University Hospital Heidelberg Heidelberg Germany

9. Institute for Pathology University Hospital Heidelberg Heidelberg Germany

10. Liver Cancer Center Heidelberg University Hospital Heidelberg Heidelberg Germany

11. Department of Internal Medicine III and Comprehensive Cancer Center, Klinikum Grosshadern Ludwig‐Maximilians‐University of Munich Munich Germany

12. Department of Molecular Medicine, Interfaculty Institute for Biochemistry University of Tübingen Tübingen Germany

13. Department of Gastroenterology, Gastrointestinal Medical Oncology University Hospital Frankfurt Frankfurt am Main Germany

14. University Cancer Center University Medical Center Mainz Germany

15. Institute of Pathology, Medical Faculty Technichal University Munich Munich Germany

16. Department of Hematology and Medical Oncology University Hospital Munich, Ludwig‐Maximilians‐University of Munich Munich Germany

17. Department of Internal Medicine I University Hospital Tübingen Tübingen Germany

18. Department of Hematology and Medical Oncology Carl Gustav Carus University Hospital Dresden Germany

19. Department of Internal Medicine I, Medical Center—University of Freiburg, Faculty of Medicine University of Freiburg Freiburg Germany

20. Comprehensive Cancer Center Freiburg (CCCF), Medical Center—University of Freiburg, Faculty of Medicine University of Freiburg Freiburg Germany

21. Institute of Medical Bioinformatics and Systems Medicine, Medical Center—University of Freiburg, Faculty of Medicine University of Freiburg Freiburg Germany

22. Institute of Pathology Charité University Medicine Berlin Berlin Germany

23. Faculty of Medicine, Charité Comprehensive Cancer Center (CCCC) Humboldt University of Berlin Berlin Germany

24. Department of hematology, medical oncology and tumor immunology Charité University Medicine Berlin Berlin Germany

25. Bridge Institute of Experimental Tumor Therapy West German Cancer Center University Hospital Essen University of Duisburg‐Essen Essen Germany

26. Division of Solid Tumor Translational Oncology German Cancer Consortium (DKTK Partner Site Essen) and German Cancer Research Center, DKFZ Heidelberg Germany

27. Department for Translational Oncology, West German Tumor Center (WTZ) Essen University Hospital Essen Germany

28. Translational Medical Oncology Faculty of Medicine and University Hospital Carl Gustav Carus Technische Universität Dresden Dresden Germany

29. Department for Translational Medical Oncology National Center for Tumor Diseases (NCT/UCC), Dresden, Germany: Germany Cancer Research Center (DKFZ), Heidelberg, Germany; Faculty of Medicine and University Hospital Carl Gustav Carus Technische Universität Dresden, Dresden, Germany; Helmholtz‐Zentrum Dresden ‐ Rossendorf (HZDR) Dresden Germany

30. German Cancer Consortium (DKTK) Dresden Germany

31. Translational Functional Cancer Genomics National Center für Tumor Diseases (NCT) and German Cancer Research Center (DKFZ) Heidelberg Germany

32. Heidelberg Institute for Stem cell Technology and Experimental Medicine (HI‐STEM) Heidelberg Germany

33. Department of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute, Ikerbasque Network Centre for Biomedical Research in Liver and Digestive Diseases (CIBERehd) San Sebastian Spain

34. Department of Biochemistry and Genetics, School of Sciences University of Navarra Pamplona Spain

35. Institute of Pathology and Neuropathology RKH Klinikum Ludwigsburg Ludwigsburg Germany

Funder

AbbVie

Deutsche Krebshilfe

Deutsche Forschungsgemeinschaft

Publisher

Wiley

Subject

Hepatology

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