Affiliation:
1. Harvard Medical School Boston Massachusetts USA
2. Dermatology Section, Division of Immunology Boston Children's Hospital Boston Massachusetts USA
Abstract
AbstractThe nummular phenotype of atopic dermatitis is clinically characterized by pruritic, coin‐shaped plaques that are frequently recalcitrant to treatment. In this study, a retrospective chart review was conducted to evaluate the effectiveness and safety of dupilumab in children with nummular lesions of dermatitis. Twelve out of 14 patients demonstrated significant clinical improvement at a median time of 2.5 months (interquartile range, 1–4) after dupilumab initiation. A single case of paradoxical psoriasiform eruption was the only side effect reported in our cohort.
Subject
Dermatology,Pediatrics, Perinatology and Child Health