Interferon-γenhances both the anti-bacterial and the pro-inflammatory response of human mast cells toStaphylococcus aureus

Author:

Swindle Emily J.1,Brown Jared M.2,Rådinger Madeleine3,DeLeo Frank R.4,Metcalfe Dean D.5

Affiliation:

1. Academic Unit of Clinical and Experimental Sciences; Faculty of Medicine; University of Southampton; University Hospital Southampton; Southampton UK

2. Department of Pharmaceutical Sciences; Skaggs School of Pharmacy and Pharmaceutical Sciences; The University of Colorado Anschutz Medical Campus; Aurora CO USA

3. Krefting Research Centre; Department of Internal Medicine and Clinical Nutrition; University of Gothenburg; Göteborg Sweden

4. Laboratory of Human Bacterial Pathogenesis; Rocky Mountain Laboratories; National Institute of Allergy and Infectious Diseases; National Institutes of Health; Hamilton MA USA

5. Laboratory of Allergic Diseases; National Institute of Allergy and Infectious Diseases; National Institutes of Health; Bethesda MD USA

Funder

Division of Intramural Research, National Institute of Allergy and Infectious Diseases

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference41 articles.

1. Mast cells;Metcalfe;Physiol Rev,1997

2. Plasticity in mast cell responses during bacterial infections;Chan;Curr Opin Microbiol,2012

3. Mast cells are activated by Staphylococcus aureus in vitro but do not influence the outcome of intraperitoneal Staphylococcus aureus infection in vivo;Ronnberg;Immunology,2014

4. Toll-like receptor 4-mediated activation of murine mast cells;McCurdy;J Leukoc Biol,2001

5. Staphylococcus δ-toxin induces allergic skin disease by activating mast cells;Nakamura;Nature,2013

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