Heme oxygenase-1 deficiency results in splenic T-cell dysregulation in offspring of mothers exposed to late gestational inflammation

Author:

Ozen Maide12ORCID,Zhao Hui1,Kalish Flora1,Yang Yang3,Folkins Ann4,Burd Irina5,Wong Ronald J.1,Stevenson David K.1

Affiliation:

1. Department of Pediatrics; Division of Neonatal and Developmental Medicine; Stanford University School of Medicine; Stanford CA USA

2. Department of Pediatrics; Johns Hopkins University; Baltimore MD USA

3. Department of Genetics; Stanford University School of Medicine; Stanford CA USA

4. Department of Pathology; Stanford University School of Medicine; Stanford CA USA

5. Department of Gynecology and Obstetrics; Integrated Research Center for Fetal Medicine; Johns Hopkins University; Baltimore MD USA

Funder

The March of Dimes Prematurity Research Center at Stanford University

The Mary L Johnson Research Fund

The Christopher Hess Research Fund

Publisher

Wiley

Subject

Obstetrics and Gynecology,Reproductive Medicine,Immunology,Immunology and Allergy

Reference56 articles.

1. Infections and brain development;Cordeiro;Obstet Gynecol Surv,2015

2. Maternal immunomodulation therapy for prevention of preterm birth and prematurity-related morbidity: the new era of immuno-perinatology;Nayak;Curr Pharm Des,2017

3. Th1/Th2/Th17 and regulatory T-cell paradigm in pregnancy;Saito;Am J Reprod Immunol,2010

4. Maternal Foxp3 expressing CD4+ CD25+ and CD4+ CD25- regulatory T-cell populations are enriched in human early normal pregnancy decidua: a phenotypic study of paired decidual and peripheral blood samples;Dimova;Am J Reprod Immunol,2011

5. Physiologic control of the functional status of Foxp3+ regulatory T cells;Mellor;J Immunol,2011

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