Alcohol consumption is associated with widespread changes in blood DNA methylation: Analysis of cross‐sectional and longitudinal data

Author:

Dugué Pierre‐Antoine123ORCID,Wilson Rory45,Lehne Benjamin6,Jayasekara Harindra17,Wang Xiaochuan1,Jung Chol‐Hee8,Joo JiHoon E.7,Makalic Enes2,Schmidt Daniel F.2,Baglietto Laura9,Severi Gianluca10,Gieger Christian45,Ladwig Karl‐Heinz511,Peters Annette4512,Kooner Jaspal S.13141516,Southey Melissa C.1317,English Dallas R.12,Waldenberger Melanie4512,Chambers John C.613141518,Giles Graham G.123,Milne Roger L.123ORCID

Affiliation:

1. Cancer Epidemiology Division Cancer Council Victoria Melbourne VIC Australia

2. Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health The University of Melbourne Parkville VIC Australia

3. Precision Medicine, School of Clinical Sciences at Monash Health Monash University Clayton VIC Australia

4. Research Unit of Molecular Epidemiology, Helmholtz Zentrum München German Research Center for Environmental Health Munich Germany

5. Institute of Epidemiology, Helmholtz Zentrum München German Research Center for Environmental Health Munich Germany

6. Department of Epidemiology and Biostatistics Imperial College London London UK

7. Colorectal Oncogenomics Group, Department of Clinical Pathology The University of Melbourne Melbourne VIC Australia

8. Melbourne Bioinformatics The University of Melbourne Parkville VIC Australia

9. Department of Clinical and Experimental Medicine University of Pisa Pisa Italy

10. CESP, INSERM U1018, Univ. Paris‐Sud, UVSQ, Université Paris‐Saclay Gustave Roussy Villejuif France

11. Klinik und Poliklinik für Psychosomatische Medizin und Psychotherapie des Klinikums Rechts der Isar Technical University of Munich Munich Germany

12. German Center for Cardiovascular Research (DZHK) Partner Site Munich Heart Alliance Munich Germany

13. Department of Cardiology Ealing Hospital Middlesex UK

14. Imperial College Healthcare NHS Trust London UK

15. MRC‐PHE Centre for Environment and Health Imperial College London London UK

16. National Heart and Lung Institute Imperial College London London UK

17. Genetic Epidemiology Laboratory, Department of Clinical Pathology University of Melbourne Melbourne VIC Australia

18. Lee Kong Chian School of Medicine Nanyang Technological University Singapore Singapore

Funder

British Heart Foundation

Bundesministerium für Bildung und Forschung

ERAB: The European Foundation for Alcohol Research

National Health and Medical Research Council

National Institute for Health Research

Wellcome

Seventh Framework Programme

National Institute on Handicapped Research

Wellcome Trust

Medical Research Council

Publisher

Wiley

Subject

Psychiatry and Mental health,Pharmacology,Medicine (miscellaneous)

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