Optimizing diagnostic algorithms to advance Hepatitis C elimination in Italy: A cost effectiveness evaluation

Author:

Marcellusi Andrea12ORCID,Mennini Francesco Saverio12ORCID,Ruf Murad3,Galli Claudio4ORCID,Aghemo Alessio56ORCID,Brunetto Maurizia R.78ORCID,Babudieri Sergio9ORCID,Craxi Antonio10ORCID,Andreoni Massimo1112ORCID,Kondili Loreta A.13ORCID

Affiliation:

1. Economic Evaluation and HTA (EEHTA) CEIS Faculty of Economics University of Rome “Tor Vergata” Rome Italy

2. Institute of Leadership and Management in Health Kingston Business School Kingston University London UK

3. Public Health, Medical Affairs Gilead Science London UK

4. Global Medical and Scientific Affairs Core Laboratory, Abbott Rome Italy

5. Department of Biomedical Sciences Humanitas University Pieve Emanuele Italy

6. Division of Internal Medicine and Hepatology Humanitas Research Hospital IRCCS Rozzano Italy

7. Internal Medicine Department of Clinical and Experimental Medicine University of Pisa Pisa Italy

8. Hepatology Unit and Laboratory of Molecular Genetics and Pathology of Hepatitis Viruses University Hospital of Pisa Pisa Italy

9. Infectious and Tropical Disease Unit Department of Medical Surgical and Experimental Sciences University of Sassari Sassari Italy

10. Gastroenterology and Hepatology Unit Department of Internal Medicine and Medical Specialties “PROMISE” University of Palermo Palermo Italy

11. Department of Systems Medicine University of Rome “Tor Vergata” Rome Italy

12. Infectious Diseases Clinic University Hospital “Tor Vergata” Rome Italy

13. Center for Global Health Istituto Superiore di Sanità Rome Italy

Funder

Gilead Sciences

Publisher

Wiley

Subject

Hepatology

Reference32 articles.

1. World Health Organization.Global Health Sector Strategy on Viral Hepatitis 2016‐2021 [Internet].2016. Available from:https://apps.who.int/iris/bitstream/10665/246177/1/WHO‐HIV‐2016.06‐eng.pdf?ua=1Accessed March 20 2021

2. European Centre for Disease Prevention and Control.Systematic review on hepatitis B and C prevalence in the EU/EEA [Internet].2016. Available from:https://www.ecdc.europa.eu/sites/default/files/media/en/publications/Publications/systematic‐review‐hepatitis‐B‐C‐prevalence.pdfAccessed March 20 2021

3. Predicted Effects of Treatment for HCV Infection Vary Among European Countries

4. The Italian Medicines Agency.AIFA Agenzia Italiana del Farmaco [Internet]. Agenziafarmaco.gov.it.2021. Available from:https://www.aifa.gov.it/‐/aggiornamento‐epatite‐cAccessed March 27 2021

5. Estimated prevalence of undiagnosed HCV infected individuals in Italy: A mathematical model by route of transmission and fibrosis progression

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