Scorpion toxin inhibits the voltage‐gated proton channel using a Zn 2+ ‐like long‐range conformational coupling mechanism-Reference-Cited by-同舟云学术

Scorpion toxin inhibits the voltage‐gated proton channel using a Zn 2+ ‐like long‐range conformational coupling mechanism

Published:2020-03-03 Issue:10 Volume:177 Page:2351-2364
ISSN:0007-1188
Container-title:British Journal of Pharmacology
language:en
Short-container-title:Br J Pharmacol

Author:

Tang Dongfang¹,Yang Yuqin²³,Xiao Zhen¹,Xu Jiahui¹,Yang Qiuchu¹,Dai Han¹,Liang Songping¹,Tang Cheng¹,Dong Hao²³^ORCID,Liu Zhonghua¹

Affiliation:

1. The National and Local Joint Engineering Laboratory of Animal Peptide Drug Development, College of Life Sciences Hunan Normal University Changsha China

2. Kuang Yaming Honors School Nanjing University Nanjing China

3. Institute for Brain Sciences Nanjing University Nanjing China

Funder

Natural Science Foundation of Jiangsu Province

Natural Science Foundation of Hunan Province

Publisher

Wiley

Subject

Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/bph.14984

Reference60 articles.

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3. The inhibition of voltage-gated H+ channel (HVCN1) induces acidification of leukemic Jurkat T cells promoting cell death by apoptosis

4. Optimization of the Additive CHARMM All-Atom Protein Force Field Targeting Improved Sampling of the Backbone ϕ, ψ and Side-Chain χ1 and χ2 Dihedral Angles

5. Targeting voltage sensors in sodium channels with spider toxins

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