Genetic predisposition to PEG-asparaginase hypersensitivity in children treated according to NOPHO ALL2008

Author:

Højfeldt Sofie G.1ORCID,Wolthers Benjamin O.2ORCID,Tulstrup Morten2ORCID,Abrahamsson Jonas3,Gupta Ramneek4,Harila-Saari Arja5,Heyman Mats6,Henriksen Louise T.1ORCID,Jónsson Òlafur G.7,Lähteenmäki Päivi M.8,Lund Bendik9,Pruunsild Kaie10,Vaitkeviciene Goda11,Schmiegelow Kjeld2,Albertsen Birgitte K.1,

Affiliation:

1. Child and Adolescent Health; Aarhus University Hospital; Aarhus Denmark

2. Department of Paediatrics and Adolescent Medicine; University Hospital Rigshospitalet; Copenhagen Denmark

3. Department of Paediatrics; Institution for Clinical Sciences; Sahlgrenska Academy; University of Gothenburg; Gothenburg Sweden

4. Department of Bio- and Health Informatics; Technical University of Denmark; Kongens Lyngby Denmark

5. Department of Women's and Children's health; Uppsala University; Uppsala Sweden

6. Department of Women's and Children's health; Childhood Cancer Research Unit; Karolinska University Hospital and Karolinska Institute; Stockholm Sweden

7. Children's Hospital; Landspitali University Hospital; Reykjavik Iceland

8. Department of Paediatric and Adolescent Medicine; Turku University Hospital and Turku University; Turku Finland

9. Department of Paediatrics; St. Olavs Hospital; Trondheim Norway

10. Department of Oncology and Haematology; University Children's Hospital; Tallinn Estonia

11. Clinic of Children's Diseases; Faculty of Medicine; Vilnius University; Vilnius Lithuania

Publisher

Wiley

Subject

Hematology

Reference53 articles.

1. Pharmacokinetics of Erwinia asparaginase after intravenous and intramuscular administration;Albertsen;Cancer Chemotherapy and Pharmacology,2001

2. Data quality control in genetic case-control association studies;Anderson;Nature Protocols,2010

3. Antibody against poly(ethylene glycol) adversely affects PEG-asparaginase therapy in acute lymphoblastic leukemia patients;Armstrong;Cancer,2007

4. Immunology of infusion reactions in the treatment of patients with acute lymphoblastic leukemia;Asselin;Future Oncology,2016

5. In vitro and in vivo killing of acute lymphoblastic leukemia cells by L-asparaginase;Asselin;Cancer Research,1989

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