A Distinct Subpopulation of Bone Marrow Mesenchymal Stem Cells, Muse Cells, Directly Commit to the Replacement of Liver Components

Author:

Katagiri H.12,Kushida Y.3,Nojima M.4,Kuroda Y.3,Wakao S.4,Ishida K.12,Endo F.12,Kume K.1256,Takahara T.2,Nitta H.2,Tsuda H.7,Dezawa M.34,Nishizuka S. S.12568

Affiliation:

1. Molecular Therapeutics Laboratory; Iwate Medical University School of Medicine; Morioka Japan

2. Department of Surgery; Iwate Medical University School of Medicine; Morioka Japan

3. Department of Anatomy and Anthropology; Tohoku University Graduate School of Medicine; Sendai Japan

4. Department of Stem Cell Biology and Histology; Tohoku University Graduate School of Medicine; Sendai Japan

5. Institute for Biomedical Sciences; Iwate Medical University; Yahaba Japan

6. Medical Innovation by Advanced Science and Technology Program; Iwate Medical University; Morioka Japan

7. Diagnostic Pathology Section, Clinical Laboratory Division; National Cancer Center Hospital; Tokyo Japan

8. Department of Surgery; Iwate Medical University School of Dentistry; Morioka Japan. Iwate Tohoku Medical Megabank Organization; Iwate Medical University; Yahaba Japan

Funder

Ministry of Education, Culture, Science and Technology

Grant-in-Aid for Scientific Research

Publisher

Wiley

Subject

Pharmacology (medical),Transplantation,Immunology and Allergy

Reference35 articles.

1. Functional integration of hepatocytes derived from human mesenchymal stem cells into mouse livers;Aurich;Gut,2007

2. New horizons for stem cell therapy in liver disease;Forbes;J Hepatol,2012

3. Concise review: Mesenchymal stem cells: Their phenotype, differentiation capacity, immunological features, and potential for homing;Chamberlain;Stem Cells,2007

4. Bone marrow mesenchymal stem cells: Biological properties and their role in hematopoiesis and hematopoietic stem cell transplantation;Pontikoglou;Stem Cell Rev,2011

5. Atypical ductular proliferation and its inhibition by transforming growth factor beta1 in the 3,5-diethoxycarbonyl-1,4-dihydrocollidine mouse model for chronic alcoholic liver disease;Preisegger;Lab Invest,1999

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