Activated microglia in ischemic stroke penumbra upregulate MCP-1 and CCR2 expression in response to lysophosphatidylcholine derived from adjacent neurons and astrocytes

Author:

Inose Yuri123,Kato Yoichiro2,Kitagawa Kazuo3,Uchiyama Shinichiro345,Shibata Noriyuki2

Affiliation:

1. Graduate School of Medicine; Tokyo Women's Medical University; Tokyo Japan

2. Department of Pathology; Tokyo Women's Medical University; Tokyo Japan

3. Department of Neurology; Tokyo Women's Medical University; Tokyo Japan

4. Clinical Research Center for Medicine; International University of Health and Welfare; Tokyo Japan

5. Center for Brain and Cerebral Vessels; Sanno Hospital and Sanno Medical Center; Tokyo Japan

Publisher

Wiley

Subject

Clinical Neurology,General Medicine,Pathology and Forensic Medicine

Reference49 articles.

1. World stroke day: one world voice for stroke;Davis;Int J Stroke,2013

2. Pathophysiological mechanisms of carotid plaque vulnerability: impact on ischemic stroke;Pelisek;Arch Immunol Ther Exp (Warsz),2012

3. Ischemic lesion volume in the subacute phase of stroke correlates with long-term functional outcome;Schiemanck;Stroke,2004

4. Ischemic lesion volume correlates with long-term functional outcome and quality of life of middle cerebral artery stroke survivors;Schiemanck;Restor Neurol Neurosci,2005

5. Relationship between ischemic lesion volume and functional status in the 2nd week after middle cerebral artery stroke;Schiemanck;Neurorehabil Neural Repair,2005

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