Adverse event potentially due to an interaction between ibrutinib and verapamil: a case report

Author:

Lambert Kuhn E.1,Levêque D.1,Lioure B.2,Gourieux B.1,Bilbault P.3

Affiliation:

1. Pharmacy; Strasbourg University Hospital; Strasbourg France

2. Hematology/Oncology Department; Strasbourg University Hospital; Strasbourg France

3. Emergency Department; Strasbourg University Hospital; Strasbourg France

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference9 articles.

1. Imbruvica ® summary of product characteristics October 2015 http://ec.europa.eu/health/documents/community-register/2015/20150703132326/anx_132326_fr.pdf

2. The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy;Honigberg;Proc Natl Acad USA,2010

3. Absorption, metabolism, and excretion of oral 14C radiolabeled ibrutinib: an open-label, phase I, single-dose study in healthy men;Scheers;Drug Metab Dispos,2015

4. Stable isotope-intravenous microdose for absolute bioavailability and effects of grapefruit juice on ibrutinib in healthy subjects;Vries;Br J Clin Pharmacol,2015

5. Population pharmacokinetic model of ibrutinib, a Bruton tyrosine kinase inhibitor, in patients with B cell malignancies;Marostica;Cancer Chemother Pharmacol,2015

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