Combined treatment of rapamycin and dietary restriction has a larger effect on the transcriptome and metabolome of liver-Reference-Cited by-同舟云学术

Combined treatment of rapamycin and dietary restriction has a larger effect on the transcriptome and metabolome of liver

Published:2013-12-05 Issue:2 Volume:13 Page:311-319
ISSN:1474-9718
Container-title:Aging Cell
language:en
Short-container-title:Aging Cell

Author:

Fok Wilson C.¹,Bokov Alex²³,Gelfond Jonathan³,Yu Zhen⁴,Zhang Yiqiang²⁵,Doderer Mark⁶,Chen Yidong³⁶⁷,Javors Martin⁸,Wood William H.⁹,Zhang Yongqing⁹,Becker Kevin G.⁹,Richardson Arlan¹²¹⁰,Pérez Viviana I.⁴¹¹

Affiliation:

1. Department of Cellular and Structural BiologyThe University of Texas Health Science Center at San Antonio San Antonio TX 78229 USA

2. Barshop Institute for Longevity and Aging StudiesThe University of Texas Health Science Center at San Antonio San Antonio TX 78229 USA

3. Department of Epidemiology & Biostatistics The University of Texas Health Science Center at San Antonio San Antonio TX 78229USA

4. Linus Pauling Institute Oregon State University Corvallis OR 97331USA

5. Department of PhysiologyThe University of Texas Health Science Center at San Antonio San Antonio TX 78229 USA

6. Greehey Children's Cancer Research Institute The University of Texas Health Science Center at San AntonioSan Antonio TX 78229 USA

7. Cancer Therapy and Research Center The University of Texas Health Science Center at San AntonioSan Antonio TX 78229 USA

8. Department of Psychiatry The University of Texas Health Science Center at San Antonio San Antonio TX 78229USA

9. National Institute on Aging Baltimore MD 21224 USA

10. Research Service Audie Murphy VA Hospital (STVHCS) San Antonio TX 78229USA

11. Department of Biochemistry and Biophysics Oregon State University Corvallis OR 97331USA

Funder

National Institutes of Health

Publisher

Wiley

Subject

Cell Biology,Aging

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/acel.12175

Reference44 articles.

1. Rapamycin increases lifespan and inhibits spontaneous tumorigenesis in inbred female mice

2. Starvation Induces Vacuolar Targeting and Degradation of the Tryptophan Permease in Yeast

3. Mechanisms of Life Span Extension by Rapamycin in the Fruit Fly Drosophila melanogaster

4. The role of oxidative damage and stress in aging

5. Identification of longevity-associated genes in long-lived Snell and Ames dwarf mice

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