DGCR8-mediated disruption of miRNA biogenesis induces cellular senescence in primary fibroblasts
Author:
Affiliation:
1. Instituto de Investigaciones Biomédicas ‘Alberto Sols’ CSIC-UAM; Madrid; Spain
2. Cell Proliferation Group; MRC Clinical Sciences Centre; Imperial College London; London; UK
Publisher
Wiley
Subject
Cell Biology,Ageing
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/acel.12117/fullpdf
Reference45 articles.
1. The tumor suppressor ING1 contributes to epigenetic control of cellular senescence;Abad;Aging Cell,2011
2. miRNA profile associated with replicative senescence, extended cell culture, and ectopic telomerase expression in human foreskin fibroblasts;Bonifacio;PLoS ONE,2010
3. Multiple microRNAs rescue from Ras-induced senescence by inhibiting p21(Waf1/Cip1);Borgdorff;Oncogene,2010
4. Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts;Brown;Science,1997
5. DiGeorge syndrome critical region 8(DGCR8) -mediated miRNA biogenesis is essential for vascular smooth muscle cell development in mice;Chen;J. Biol. Chem.,2012
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