The use of cerebral computed tomographic angiography as an ancillary investigation to support a clinical diagnosis of death using neurological criteria: a consensus guideline

Author:

Thomas E. O.1ORCID,Manara A.2ORCID,Dineen R. A.34ORCID,Mortimer A.5ORCID,Aziz O.6ORCID,Dean P.7,Elliott P.8,Summers D. M.910ORCID,Whitfield P. C.11ORCID,Hutchinson P. J.12ORCID,Gardiner D.13ORCID

Affiliation:

1. Department of Intensive Care Medicine University Hospitals NHS Trust Plymouth UK

2. Department of Intensive Care Medicine North Bristol NHS Trust Bristol UK

3. Faculty of Medicine and Health Sciences University of Nottingham UK

4. Department of Radiology Nottingham University Hospital NHS Trust Nottingham UK

5. Department of Radiology North Bristol NHS Trust Bristol UK

6. Bristol Royal Hospital for Children and University Hospital Bristol and Weston NHS Foundation Trust Bristol UK

7. Department of Intensive Care Medicine and Anaesthesia East Lancashire Hospitals NHS Trust Lancashire UK

8. Royal College of Anaesthetists London UK

9. Department of Neuroradiology NHS Lothian Edinburgh UK

10. University of Edinburgh UK

11. South West Neurosurgery Centre University Hospitals NHS Trust Plymouth UK

12. Department of Neurosurgery University of Cambridge, Cambridge University Hospitals NHS Foundation Trust Cambridge UK

13. Department of Intensive Care Medicine Nottingham University Hospital NHS Trust Nottingham UK

Abstract

SummaryThis multidisciplinary consensus statement was produced following a recommendation by the Faculty of Intensive Care Medicine to develop a UK guideline for ancillary investigation, when one is required, to support the diagnosis of death using neurological criteria. A multidisciplinary panel reviewed the literature and UK practice in the diagnosis of death using neurological criteria and recommended cerebral CT angiography as the ancillary investigation of choice when death cannot be confirmed by clinical criteria alone. Cerebral CT angiography has been shown to have 100% specificity in supporting a diagnosis of death using neurological criteria and is an investigation available in all acute hospitals in the UK. A standardised technique for performing the investigation is described alongside a reporting template. The panel were unable to make recommendations for ancillary testing in children or patients receiving extracorporeal membrane oxygenation.

Publisher

Wiley

Subject

Anesthesiology and Pain Medicine

Reference18 articles.

1. CT Angiography for Brain Death Diagnosis

2. Academy of Medical Royal Colleges.A code of practice for the diagnosis and confirmation of death.2010.www.aomrc.org.uk/reports‐guidance/ukdec‐reports‐and‐guidance/code‐practice‐diagnosis‐confirmation‐death(accessed 08/11/2022).

3. Determination of Brain Death/Death by Neurologic Criteria

4. Australia and New Zealand Intensive Care Society.Statement on death and organ donation (edition 4.1).2021.https://www.anzics.com.au/wp‐content/uploads/2022/04/ANZICS‐Statement‐on‐Death‐and‐Organ‐Donation.pdf(accessed 08/11/2022).

5. Implementation of Computed Tomography Angiography (CTA) and Computed Tomography Perfusion (CTP) in Polish Guidelines for Determination of Cerebral Circulatory Arrest (CCA) during Brain Death/Death by Neurological Criteria (BD/DNC) Diagnosis Procedure

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