Amphiphilic suramin dissolves Matrigel, causing an ‘inhibition’ artefact withinin vitroangiogenesis assays

Author:

Prigozhina Natalie L.12,Heisel Andrew J.1,Seldeen Jordan R.1,Cosford Nicholas D. P.1,Price Jeffrey H.12

Affiliation:

1. Sanford-Burnham Medical Research Institute; La Jolla CA USA

2. Vala Sciences Inc.; San Diego CA USA

Publisher

Wiley

Subject

Cell Biology,Molecular Biology,Pathology and Forensic Medicine

Reference22 articles.

1. Angiogenesis in wound healing;Arnold;Pharmacol. Ther.,1991

2. A novel in vitro assay for human angiogenesis;Brown;Lab. Invest.,1996

3. Vasculogenesis and angiogenesis in the early human placenta;Demir;Acta Histochem.,2007

4. Anti-angiogenic activity of selected receptor tyrosine kinase inhibitors, PD166285 and PD173074: implications for combination treatment with photodynamic therapy;Dimitroff;Invest. New Drugs,1999

5. Antiangiogenic and antiproliferative activity of suramin analogues;Gagliardi;Cancer Chemother. Pharmacol.,1998a

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