Epigenetic control of early neurodegenerative events in diabetic retinopathy by the histone deacetylase SIRT6

Author:

Zorrilla-Zubilete María A.1,Yeste Ada2,Quintana Francisco J.23,Toiber Debra4,Mostoslavsky Raul53,Silberman Dafne M.1ORCID

Affiliation:

1. Centro de Estudios Farmacológicos y Botánicos (CEFYBO-CONICET); 1ª Cátedra de Farmacología; Facultad de Medicina; UBA; Buenos Aires Argentina

2. Brigham and Women's Hospital; Harvard Medical School; Boston Massachusetts USA

3. Broad Institute of MIT and Harvard; Cambridge Massachusetts USA

4. Department of Life Sciences; The Zlotowski Center for Neuroscience; Ben-Gurion University of the Negev; Beer-Sheva Israel

5. The Massachusetts General Hospital Cancer Center; Harvard Medical School; Boston Massachusetts USA

Funder

Agencia Nacional de Promoción Científica y Tecnológica

Universidad de Buenos Aires

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Biochemistry

Reference41 articles.

1. Diabetic retinopathy: loss of neuroretinal adaptation to the diabetic metabolic environment;Abcouwer;Ann. N.Y. Acad. Sci.,2014

2. Role of vascular endothelial growth factor in diabetic vascular complications;Aiello;Kidney Int.,2000

3. Vascular endothelial growth factor is present in glial cells of the retina and optic nerve of human subjects with non-proliferative diabetic retinopathy;Amin;Invest. Ophthalmol. Vis. Sci.,1997

4. Enhanced insulin sensitivity in skeletal muscle and liver by physiological overexpression of SIRT6;Anderson;Mol. Metab.,2015

5. Sirtuin 6 expression and inflammatory activity in diabetic atherosclerotic plaques: effects of incretin treatment;Balestrieri;Diabetes,2015

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