A prospective randomised placebo-controlled study of the impact of dutasteride/tamsulosin combination therapy on sexual function domains in sexually active men with lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH)

Author:

Roehrborn Claus G.1,Manyak Michael J.2,Palacios-Moreno Juan Manuel3ORCID,Wilson Timothy H.4,Roos Erik P.M.5,Santos Javier Cambronero6,Karanastasis Dimitrios7,Plastino Janet8,Giuliano François9,Rosen Raymond C.10

Affiliation:

1. Department of Urology; University of Texas (UT) Southwestern Medical Center; Dallas TX USA

2. GlaxoSmithKline (GSK); Washington DC USA

3. GSK; Madrid Spain

4. PAREXEL International; Durham NC USA

5. Antonius Ziekenhuis Sneek; Sneek The Netherlands

6. Hospital Universitario Infanta Leonor; Madrid Spain

7. Urologic Clinic; General Hospital of Athens ‘Elpis’; Athens Greece

8. GSK; Collegeville PA USA

9. Neuro-Urology R. Poincare Hospital AP-HP; Garches; UMR1179 Inserm-UVSQ-Paris Saclay University; Paris, France France

10. New England Research Institutes; Watertown MA USA

Funder

GlaxoSmithKline

Publisher

Wiley

Subject

Urology

Reference35 articles.

1. Benign prostatic hyperplasia: risk factors and management;Nash;GM,2010

2. Ejaculatory dysfunction in men with lower urinary tract symptoms suggestive of benign prostatic hyperplasia;Rosen;BJU Int,2009

3. The effects of combination therapy with dutasteride and tamsulosin on clinical outcomes in men with symptomatic benign prostatic hyperplasia: 4-year results from the CombAT study;Roehrborn;Eur Urol,2010

4. Gravas S Bach T Bachmann A et al. EAU guidelines on management of non-neurogenic male lower urinary tract symptoms (LUTS), incl. benign prostatic obstruction (BPO) 2016 https://uroweb.org/wp-content/uploads/Non-Neurogenic-Male-LUTS_2705.pdf

5. Understanding patient and physician perceptions of benign prostatic hyperplasia in Europe: The Prostate Research on Behaviour and Education (PROBE) Survey;Emberton;Int J Clin Pract,2008

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