Testicular hypofunction caused by activating p53 expression induced by reactive oxygen species in varicocele rats

Author:

Liang M.12,Wen J.2,Dong Q.3,Zhao L.-G.4,Shi B.-K.1

Affiliation:

1. Department of Urology; Qilu Hospital; Shandong University; Jinan China

2. Reproductive Medical Center; The Second Hospital Affiliated to Shandong University of Traditional Chinese Medicine; Jinan China

3. National Health and Family Planning Commission of the People's Republic of China; Beijing China

4. Reproductive Medicine Research Center; The Sixth Affiliated Hospital of Sun Yat-sen University; Guangzhou China

Funder

Family Planning Commission of Shandong Province

Natural Science Fund project in Shandong province

Publisher

Wiley

Subject

Urology,Endocrinology,General Medicine

Reference33 articles.

1. Analysis of lipid peroxidation mechanisms in human spermatozoa;Aitken;Mol Reprod Dev,1993

2. Analysis of sperm movement in relation to the oxidative stress created by leukocytes in washed sperm preparations and seminal plasma;Aitken;Hum Reprod,1995a

3. Redox regulation of tyrosine phosphorylation in human spermatozoa and its role in the control of human sperm function;Aitken;J Cell Sci,1995b

4. A novel signal transduction cascade in capacitating human spermatozoa characterised by a redox-regulated, cAMP mediated induction of tyrosine phosphorylation;Aitken;J Cell Sci,1998

5. Stabilisation of wild-type p53 by hypoxia-inducible factor 1alpha;An;Nature,1998

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