Incidence and relative risk of grade 3 and 4 diarrhoea in patients treated with capecitabine or 5-fluorouracil: a meta-analysis of published trials

Author:

Iacovelli Roberto12,Pietrantonio Filippo1,Palazzo Antonella12,Maggi Claudia12,Ricchini Francesca1,de Braud Filippo1,Di Bartolomeo Maria1

Affiliation:

1. Department of Meical Oncology, Fondazione IRCCS; Istituto Nazionale Tumori; Milan Italy

2. PhD Program; Department of Radiology Oncology and Human Pathology; Sapienza University of Rome; Rome Italy

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference53 articles.

1. Preliminary studies of a novel oral fluoropyrimidine carbamate: capecitabine;Budman;J Clin Oncol,1998

2. FDA Capecitabine product information http://www.accessdata.fda.gov/drugsatfda_docs/label/2011/020896s026lbl.pdf

3. EMA Capecitabine product information http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/000316/WC500058151.pdf

4. Common terminology criteria for adverse events http://evs.nci.nih.gov/ftp1/CTCAE/CTCAE_4.03_2010-06-14_QuickReference_5x7.pdf

5. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement;Liberati;BMJ,2009

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