Sensitivity and Reliability of Halothane-anaesthetizedMicrominipigsto Assess Risk of Drug-induced Long QT Syndrome
Author:
Affiliation:
1. Department of Pharmacology; Toho University Graduate School of Medicine; Ota-ku, Tokyo Japan
2. Department of Pharmacology; Faculty of Medicine; Toho University; Ota-ku, Tokyo Japan
Funder
Japan Agency for Medical Research and Development
Japan Society for the Promotion of Science London
Publisher
Wiley
Subject
Pharmacology,Toxicology,General Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/bcpt.12838/fullpdf
Reference38 articles.
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2. Sensitive and reliable proarrhythmia in vivo animal models for predicting drug-induced torsades de pointes in patients with remodelled hearts;Sugiyama;Br J Pharmacol,2008
3. The utility of the minipig as an animal model in regulatory toxicology;Bode;J Pharmacol Toxicol Methods,2010
4. Microminipig, a non-rodent experimental animal optimized for life science research: preface;Kaneko;J Pharmacol Sci,2011
5. Microminipig, a non-rodent experimental animal optimized for life science research. In vivo proarrhythmia models of drug-induced long QT syndrome: development of chronic atrioventricular block model of microminipig;Sugiyama;J Pharmacol Sci,2011
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