Pregnane‐based steroids are novel positive NMDA receptor modulators that may compensate for the effect of loss‐of‐function disease‐associated <i>GRIN</i> mutations-Reference-Cited by-同舟云学术

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Pregnane‐based steroids are novel positive NMDA receptor modulators that may compensate for the effect of loss‐of‐function disease‐associated GRIN mutations

Published:2022-04-08 Issue:15 Volume:179 Page:3970-3990
ISSN:0007-1188
Container-title:British Journal of Pharmacology
language:en
Short-container-title:British J Pharmacology

Author:

Kysilov Bohdan¹²,Hrcka Krausova Barbora¹,Vyklicky Vojtech¹,Smejkalova Tereza¹^ORCID,Korinek Miloslav¹,Horak Martin¹,Chodounska Hana³,Kudova Eva³,Cerny Jiri¹^ORCID,Vyklicky Ladislav¹^ORCID

Affiliation:

1. Institute of Physiology CAS Prague 4 Czech Republic

2. Third Faculty of Medicine Charles University in Prague Prague 10 Czech Republic

3. Institute of Organic Chemistry and Biochemistry CAS Prague 6 Czech Republic

Funder

Akademie Věd České Republiky

Grantová Agentura České Republiky

Grantová Agentura, Univerzita Karlova

European Regional Development Fund

Technology Agency of the Czech Republic

Publisher

Wiley

Subject

Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/bph.15841

Reference79 articles.

1. GROMACS: High performance molecular simulations through multi-level parallelism from laptops to supercomputers

2. Electronic structure calculations on workstation computers: The program system turbomole

3. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Ion channels

4. From bedside‐to‐bench: What disease‐associated variants are teaching us about the NMDA receptor

5. Direct Measure of the De Novo Mutation Rate in Autism and Schizophrenia Cohorts

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1. Disease-Associated Variants in GRIN1, GRIN2A and GRIN2B genes: Insights into NMDA Receptor Structure, Function, and Pathophysiology;Physiological Research;2024-08-31

2. 5β-Dihydrosteroids: Formation and Properties;International Journal of Molecular Sciences;2024-08-14

3. Characterization of Mice Carrying a Neurodevelopmental Disease-Associated GluN2B(L825V) Variant;The Journal of Neuroscience;2024-06-26

4. Rescuing tri-heteromeric NMDA receptor function: the potential of pregnenolone-sulfate in loss-of-function GRIN2B variants;Cellular and Molecular Life Sciences;2024-05-25

5. Disease-associated nonsense and frame-shift variants resulting in the truncation of the GluN2A or GluN2B C-terminal domain decrease NMDAR surface expression and reduce potentiating effects of neurosteroids;Cellular and Molecular Life Sciences;2024-01-12

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